Seroprevalence and Risk Factors of Coxiella Burnetii Infection Among High-Risk Population in Center of Iran, a Neglected Health Problem Publisher Pubmed



Nokhodian Z¹ ; Ataei B¹ ; Moradi A² ; Yaran M³ ; Hoseini SG¹ ; Feizi A⁴ ; Sherkat R⁵
Source: Acta Tropica Published:2017

Abstract

In order to evaluate the prevalence of antibodies against phase I and II antigens of Coxiella Burnetii and to identify related risk factors among high-risk groups in the center of Iran, a serological survey was performed in Isfahan County. In a cross-sectional study, 401 sera were collected from slaughterhouse workers, butchers, farmers and veterinarians in spring 2015. Samples were tested for specific immunoglobulin G (IgG) antibodies against phase I and II of C. burnetii by indirect immunofluorescence assay. A checklist was fulfilled to document demographic information. Univariate analysis and multivariable binary logistic regression model were used to analyze data. IgG antibodies against phases I and II of C. burnetii were detected in 19% and 36.9% of participants, respectively. The overall seropositivity (IgG against phase I and/or II) was 43.1%. The present study shows a high seroprevalence of C. burnetii infection among high-risk population in center of Iran. It is suggested to carry out occupational health monitoring programs for individuals who may be exposed to C. burnetii. © 2017 Elsevier B.V.