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What Nephrolopathologists Need to Know About Antiphospholipid Syndrome-Associated Nephropathy: Is It Time for Formulating a Classification for Renal Morphologic Lesions? Publisher



Mubarak M1 ; Nasri H2
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Authors Affiliations
  1. 1. Department of Histopathology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan
  2. 2. Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Nephropathology Published:2014


Abstract

Context: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder which commonly affects kidneys. Evidence Acquisitions: Directory of Open Access Journals (DOAJ), Google Scholar, PubMed (NLM), LISTA (EBSCO) and Web of Science have been searched. Results: There is sufficient epidemiological, clinical and histopathological evidence to show that antiphospholipid syndrome is a distinctive lesion caused by antiphospholipid antibodies in patients with different forms of antiphospholipid syndrome. It is now time to devise a classification for an accurate diagnosis and prognostication of the disease. Conclusions: Now that the morphological lesions of APSN are sufficiently well characterized, it is prime time to devise a classification which is of diagnostic and prognostic utility in this disease. © 2014, Society of Diabetic Nephropathy Prevention. All rights reserved.
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