Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Effect of Prangos Ferulacea Vaginal Cream on Accelerating the Recovery of Bacterial Vaginosis: A Randomized Controlled Clinical Trial Pubmed



Azadpour Motlagh A1 ; Dolatian M2 ; Mojab F3 ; Nasiri M4 ; Ezatpour B5 ; Sahranavard Y6 ; Shakiba H7 ; Rahimy B8 ; Ghanati K9
Authors
Show Affiliations
Authors Affiliations
  1. 1. International Branch of Shahid Beheshti, University of Medical Sciences, Tehran, Iran
  2. 2. Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Paramedical, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Razi Herbal, Medicines Research Center, Lorestan University of Medical Sciences, Lorestan, Iran
  6. 6. Department of Paramedical, School of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
  7. 7. Department of Paramedical, Islamic Azazd University Borojerrd Branch, Borojerrd, Iran
  8. 8. Department of Nursing and Midwifery, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
  9. 9. National Nutrition and Food Technology Research Institute, Department of the International Affairs of Shahid, Beheshti University of Medical Sciences, Tehran, Iran

Source: International Journal of Community Based Nursing and Midwifery Published:2018


Abstract

Background: The present study was conducted on the effect of prangos ferulacea vaginal cream on accelerating the recovery of bacterial vaginosis. Methods: This randomized controlled clinical trial was conducted on 100 non-pregnant women referring to health centers affiliated to Lorestan University of Medical Sciences in 2016 with the diagnosis of bacterial vaginosis based on the patient’s complaints, Amsel’s clinical criteria, and the Nugent microscopic criteria. The women were randomly divided into two groups of 50. One group was treated with oral metronidazole plus Prangos ferulacea vaginal cream and the other with oral metronidazole plus a placebo vaginal cream for seven days. The patient’s complaints, Amsel’s clinical criteria and the Nugent microscopic criteria were assessed seven days after treatment. The data were analyzed using SPSS, version 20, with a significance level of 0.05. Results: The response to oral metronidazole plus Prangos ferulacea vaginal cream treatment was 94% according to Amsel’s clinical criteria and 88% according to the Nugent microscopic criteria. The response to oral metronidazole plus placebo vaginal cream treatment was 94% according to Amsel’s criteria and 86% according to the Nugent criteria. The analysis of the patients’ complaints, Amsel’s clinical criteria and the Nugent microscopic criteria showed significant differences in each group before and after the treatment. Conclusion: This trial showed that Prangos ferulacea vaginal cream accelerated the recovery of bacterial vaginosis of patients with bacterial vaginosis. It can be used effectively as a complementary treatment with oral metronidazole in cases of medication resistance and also in people wishing to use herbal remedies. © 2018, Shriaz University of Medical Sciences. All rights reserved.
Related Docs
View other Related Docs
1. Prevalence of the Genital Tract Bacterial Infections After Vaginal Reconstructive Surgery, Pakistan Journal of Biological Sciences (2014)
2. The Comparative Study of Anti-Fungal Effect of Pharmaceutical Products Containing Hydroalcoholic Extract of Echinophora Platyloba Dc and Fluconazole in Women With Chronic Recurrent Vaginitis Caused by Candida Albicans, Journal of Research in Medical Sciences (2012)
3. A Comparative Study of Vaginal Estrogen Cream and Sustained-Release Estradiol Vaginal Tablet (Vagifem) in the Treatment of Atrophic Vaginitis in Isfahan, Iran in 2010-2012, Journal of Research in Medical Sciences (2015)
4. Clinical and Mycological Study of Vulvovaginal Candidiasis (Vvc); Identification of Clinical Isolates by Polymerase Chain Reaction-Fragment Size Polymorphyim (Pcr-Fsp) Technique, Archives of Clinical Infectious Diseases (2017)
5. Development of a Latex Agglutination Test As a Simple and Rapid Method for Diagnosis of Trichomonas Vaginalis Infection, Avicenna Journal of Medical Biotechnology (2010)
6. The Relationship Between Symptomatic Vaginal Candidiasis and Lactobacillus Flora, Using Methenamine Silver Staining Method, Rawal Medical Journal (2009)
7. Effect of Ethanolic and Watery Extract of Aerial Parts of Stachys Lavandulifolia on Trichomonas Vaginalis, in Vitro, Journal of Medicinal Plants (2012)
8. Comparison of the Therapeutic Effects of Garcin® and Fluconazole on Candida Vaginitis, Singapore Medical Journal (2015)
Experts (# of related papers)
View all Related Experts
Hossein Yousofi Darani (4)
Parvin Dehghan (3)
Other Related Docs
9. The Matching Rate of the Frequency of the Isolated Candida Species Calculated by Morphological and Molecular Methods in Patients With Vaginitis, Journal of Isfahan Medical School (2017)
10. The Frequency of Streptococcus Agalactiae in the Vaginal Secretions of Women With Abortion at Gynecology and Infertility Medical Centers in Isfahan City, Journal of Isfahan Medical School (2024)
11. Rapid Differential Diagnosis of Vaginal Infections Using Gold Nanoparticles Coated With Specific Antibodies, Medical Microbiology and Immunology (2019)
12. Treatment Approach to Leucorrhea in Traditional Iranian Medicine and Conventional Medicine, Iranian Journal of Obstetrics, Gynecology and Infertility (2016)
13. Evaluation of the Therapeutic Effect of 15 Ppm Silver Nanoparticle Spray Compared to Clotrimazole 1% on Candida Vaginitis: A Randomized Controlled Clinical Trial, Journal of Family and Reproductive Health (2023)
14. Cervicovaginal Microbial Flora in Methenamine Silver Staining Method, Journal of Research in Medical Sciences (2006)
15. Effect of Evening Primrose Vaginal Capsule on Cervix Preparation and Duration of First Stage of Labor in Nulliparous Women Referred to Fatemieh Hospital in Hamadan, Iran: A Single-Blind Randomized Controlled Trial, Current Drug Research Reviews (2022)
16. Comparative Evaluation of Ketoconazole Tablet and Topical Ketoconazole 2% in Orabase in Treatment of Candida-Infected Denture Stomatitis, Journal of Contemporary Dental Practice (2010)
17. A Comparative Study on the Effect of Artemisia and Clotrimazole Vaginal Cream on Vaginal Candida Infection on Non-Pregnant Women in Fertile Age in Mashhad in 2016-2017: A Triple Blind Clinical Trial, Journal of Medicinal Plants (2019)
18. Comparative Efficacy of Probiotic Yoghurt and Clindamycin in Treatment of Bacterial Vaginosis in Pregnant Women: A Randomized Clinical Trial, Journal of Maternal-Fetal and Neonatal Medicine (2012)
19. Effects of Oral Probiotic Supplements on the Rate of Vaginal Colonization of Group B Streptococcus in Pregnant Women: A Clinical Trial Study, Avicenna Journal of Clinical Microbiology and Infection (2024)
20. Molecular Study of Gardnerella Vaginalis Isolated From Vaginal Discharge of Women Referring to Gynecology Clinics in Chaharmahal and Bakhtiari, Iran, in 2017, Archives of Clinical Infectious Diseases (2021)
21. Diagnosis of Candida Species Isolated From Patients With Vaginal Candidiasis and Healthy Individuals Based on Clinical Symptoms and Paraclinical Evidences, Journal of Isfahan Medical School (2012)