The Pathologic Assessment of Breast Masses, in Al-Zahra Hospital, Isfahan; [یزرا بای یژولوتاپ هدوت اهی نیعجارم رد ناتسپ یشزومآ ناتسرامیب ناهفصا )س(ارهزلا] Publisher

Summary: What did 522 breast biopsies reveal? An Isfahan hospital study found invasive ductal carcinoma dominated malignant findings, while fibrocystic changes led benign lesions. #BreastCancer #Pathology

Derakhshan M ; Eskandari S ; Taab A
Source: Journal of Isfahan Medical School Published:2026

Abstract

Background: Breast cancer is the most common cancer diagnosed in the world. Despite numerous advances, its recurrence is still a big challenge; Based on this, the study was conducted with the aim of evaluating the pathology of breast masses in patients of Al-Zahra Teaching Hospital, Isfahan. Methods: In this cross-sectional study, information related to age, sex and pathology of breast masses of 522 patients who referred to Alzahra Hospital in Isfahan for examination of breast lesions between 2014 and 2019 were collected and analyzed. All these patients had undergone breast biopsy. Data were analyzed by Student's t test and described by presenting frequency, percentage, mean and standard deviation. Findings: A total of 522 patients with mean age 40.42 years were included in the study, 480 (92%) were women. Invasive ductal carcinoma (74%) and in situ ductal carcinoma (14%) were the most frequent. Other pathologies were respectively 284 (87.9%) cases of benign tumoral lesions with the predominance of two fibrocystic lesions (129 people) and fibroadenoma (121 people), were inflammatory types 28 (8.7%) cases and gynecomastia 11 (3.4%) cases. Conclusion: According to the findings of this study, the prevalence of breast cancer in people under 40 years old is high in Iran; Therefore, it is recommended to investigate the risk factors in Iranian women and spread public education. © 2026, Isfahan University of Medical Sciences(IUMS). All rights reserved.