Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets

Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets Publisher

Nickaeen N¹ ; Ghaisari J¹ ; Gheisari Y² ; Moein S²

Show Affiliations

1. Dept. of Electrical and Computer Eng., Isfahan University of Technology, Isfahan, 84156-83111, Iran
2. Regenerative Medicine Lab, Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: ICEE 2015 - Proceedings of the 23rd Iranian Conference on Electrical Engineering Published:2015

Abstract

Cell growth is controlled by some factors known as growth factors. One of these growth factors is a substance called TGF-β. Any malfunction in the system which growth factors perform in, results in drastic cell growth thus cell death. The aim of this study is to control the system of TGF-β growth factor in the case of fibrosis, a condition created by malfunction in the pathway of TGF-β. A model of TGF-β pathway is proposed using standard Petri Nets. Then a control is proposed not only to control the amount of TGF-β in the pathway but also to observe the law of conservation of matter as the absolute rule in biological systems. The results clearly show the control of TGF-β concentration in the pathway. The research may provide a basis for drug design and determination of target reactants to control fibrosis. © 2015 IEEE.

2. Protective Effects of Combined Losartan and Nilotinib on Carbon Tetrachloride (Ccl4)-Induced Liver Fibrosis in Rats, Drug and Chemical Toxicology (2020)

Experts (# of related papers)

Shaghayegh Haghjooy Javanmard (1)

Adel Mohammadalipour Malakshah (1)

Style	Citing Format
MLA	Nickaeen N, et al.. "Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets." ICEE 2015 - Proceedings of the 23rd Iranian Conference on Electrical Engineering, vol. 10, no. , 2015, pp. 38-43.
APA	Nickaeen N, Ghaisari J, Gheisari Y, Moein S (2015). Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets. ICEE 2015 - Proceedings of the 23rd Iranian Conference on Electrical Engineering, 10(), 38-43.
Chicago	Nickaeen N, Ghaisari J, Gheisari Y, Moein S. "Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets." ICEE 2015 - Proceedings of the 23rd Iranian Conference on Electrical Engineering 10, no. (2015): 38-43.
Harvard	Nickaeen N et al. (2015) 'Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets', ICEE 2015 - Proceedings of the 23rd Iranian Conference on Electrical Engineering, 10(), pp. 38-43.
Vancouver	Nickaeen N, Ghaisari J, Gheisari Y, Moein S. Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets. ICEE 2015 - Proceedings of the 23rd Iranian Conference on Electrical Engineering. 2015;10():38-43.
BibTex	@article{ author = {Nickaeen N and Ghaisari J and Gheisari Y and Moein S}, title = {Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets}, journal = {ICEE 2015 - Proceedings of the 23rd Iranian Conference on Electrical Engineering}, volume = {10}, number = {}, pages = {38-43}, year = {2015} }
RIS	TY - JOUR AU - Nickaeen N AU - Ghaisari J AU - Gheisari Y AU - Moein S TI - Modeling and Controlling Tgf-P Pathway Using Standard Petri Nets JO - ICEE 2015 - Proceedings of the 23rd Iranian Conference on Electrical Engineering VL - 10 IS - SP - 38 EP - 43 PY - 2015 ER -

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