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Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings



Nasri H1 ; Rafieiankopaei M2
Authors
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Authors Affiliations
  1. 1. Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

Source: Iranian Journal of Pediatrics Published:2014

Abstract

Metformin, an oral anti-diabetic agent in the biguanide class is a widely prescribed drug to treat high blood glucose in patients with type 2 diabetes mellitus. Metformin has three different roles, including blood glucose regulatory effect, protection of kidney tubular cell by acting as an effective antioxidant and finally ameliorative effect on diabetic kidney disease through saving the podocytes. Therefore, diabetic patients may benefit from all of these three distinct ameliorative effects. © 2014 by Pediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical Sciences, All rights reserved.
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