Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Intravenous Pamidronate for Refractory Lymphedema



Beigi AA1 ; Sadeghi AM2 ; Masoudpour H3 ; Shirazinejad S4 ; Mottaghi P5
Authors

Source: Iranian Red Crescent Medical Journal Published:2011

Abstract

Background: Based on beneficial reports of pamidronate use for reflex sympathetic dystrophy in reduction of pain and swelling, this drug can be studied as a novel treatment for refractory lymphedema. This study aims to determine the effectiveness of pamidronate on lymphedema and its possible side effects. Methods: Twelve cases of lower limb refractory lymphedema were enrolled. They received intravenous pamidronate monthly for 3 consecutive months and were followed by measuring any discomfort with visual analog scale (VAS) and physician global assessment, based on objective signs of limb volume and circumference. Results: The limb volume, circumference, and satisfaction of the patients improved significantly. Conclusion: Pamidronate when is added to conservative treatments may reduce lymphedema and improve the patient's comfort. © Iranian Red Crescent Medical Journal.