Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Dietary Polyphenols for Atherosclerosis: A Comprehensive Review and Future Perspectives Publisher Pubmed



Bahramsoltani R1, 2 ; Ebrahimi F3 ; Farzaei MH4, 5 ; Baratpourmoghaddam A3 ; Ahmadi P3 ; Rostamiasrabadi P6 ; Rasouli Amirabadi AH3 ; Rahimi R1, 2
Authors

Source: Critical Reviews in Food Science and Nutrition Published:2019


Abstract

Atherosclerosis is one of the most prevalent reasons for premature death in adults. Despite the several conventional drugs in the market; many patients are not completely treated. Here we comprehensively review current clinical evidence regarding the efficacy of dietary polyphenols in atherosclerosis and related complications. PubMed, Cochrane library and Scopus were searched from inception until August 2016 to obtain clinical trials in which polyphenols were evaluated in cardiovascular parameters related to atherosclerosis. From total of 13031 results, 49 clinical trials were finally included. Tyrosol derivatives from virgin olive oil, catechins and theaflavins from green and black tea, cocoa polyphenols, and red grape resveratrol, as well as anthocyanins were the most studied polyphenolic compounds which could regulate lipid profile, inflammation and oxidative stress, blood pressure, endothelial function, and cell adhesion molecules. The most important limitations of the included trials were small sample size, short follow up, and unqualified methodology. Future well-designed clinical trials are necessary to provide better level of evidence for clinical decision making. © 2017, © 2017 Taylor & Francis Group, LLC.
Other Related Docs