Incidence of Colorectal Cancer and Adenomatous Polyps After a Two-Step Screening in Isfahan Province, Iran in 2018 Publisher Pubmed



Soodejani MT¹ ; Mirzaei H² ; Manesh MM³ ; Tabatabaei SM^{4, 5, 6} ; Ghaderi A⁷
Source: Journal of Gastrointestinal Cancer Published:2020

Abstract

Purpose: The aim of this study was to estimate the incidence of colorectal cancers in Iran. The results of this study are based on a screening program that is being implemented in Isfahan province. Material and Methods: In this study, about 137,000 people were screened for colorectal cancer and adenomatous polyps in 2 steps during the year 2018. Results: Based on the findings of this study, the incidence of adenomatous polyps was reported to be 389 (95% CI, 365–422) per 100,000 population. The incidence of adenomatous polyps was reported to be 483 (95% CI, 446–520) and 316 (95% CI, 286–346) in men and women, respectively (p < 0.001). Also, the incidence of colorectal cancer was reported to be 33 (95% CI, 23–42) per 100,000 population. The incidence of colorectal cancer in men and women was reported to be 41 (95% CI, 30–51) and 26 (95% CI, 17–34), respectively, indicating a statistically non-significant difference (p = 0.29). Conclusion: Based on the result of this study, despite a low participation rate of the target population in the screening program, the incidence of adenomatous polyps and colorectal cancer is relatively high in the average-risk population. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.