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Patient Outcome in Primary Peritoneal Dialysis Patients Versus Those Transferred From Hemodialysis and Transplantation Publisher Pubmed



Najafi I1 ; Hosseini M1 ; Atabac S2 ; Sanadgol H3 ; Majelan NN4 ; Seirafian S5 ; Naghibi M6 ; Makhdoumi K7 ; Saddadi F1 ; Soleymanian T1
Authors

Source: International Urology and Nephrology Published:2012


Abstract

Background: According to the concept of integrated care, renal transplantation, peritoneal dialysis (PD), and hemodialysis (HD) should be considered three complementary methods of renal replacement therapy. This study tried to evaluate patient outcomes in three different groups of PD patients, namely primary PD patients, those transferred to PD with failing kidney transplant, and those transferred to PD from HD. Method From January 1, 1995, to end of 2006 from 26 PD centers, 1,355 patients including demographic, clinical and laboratory data, which were monthly collected through questionnaires, were enrolled in the study. We compared patients' characteristics, factors affecting patient survival, and patient outcomes between primary PD patients (group 1, n = 1,067), patients transferred from transplantation (group 2, n = 43) and those transferred from HD (group 3, n = 245), which had been on HD for at least 3 months before switching to PD. Results: There was no difference in the proportion of patients with diabetes in the three groups. Overall, 238 patients (17.5%) were transferred to HD but there was no significant difference in PD technique survival on between the three groups. Death occurred in 256 (24%), 3 (7%) and 65 (26.5%) subjects in groups 1, 2 and 3, respectively. Most patients (81.5%) in group 2 underwent re-transplantation. The Kaplan-Meier survival rates were not different between the three groups. In the Cox multiple regression model, age, presence of diabetes and serum albumin level significantly influenced patient survival. Conclusion: We concluded that PD could be considered safe for patients experiencing complications on HD, as well as for those with renal transplantation. © Springer Science+Business Media, B.V. 2011.
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