Tehran University of Medical Sciences

Science Communicator Platform

Faculty Members have conducted research related to the Hab-O Shefa, a Persian Medicine Compound for Maintenance Treatment of Opioid Dependence: Randomized Placebo-Controlled Clinical Trial
Mehri Kadkhodaei
Mehri Kadkhodaei

Professor of Physiology

Department Physiology

School of Medicine

Tehran University of Medical Sciences

All Documents
1. Co-Administration of Subtherapeutic Doses of Yohimbine and Nahs Potentially Ameliorates Ckd-Induced Necroptosis by Modulating Raas/Ros Imbalance, Sympathetic Overactivity, and Inflammation, Naunyn-Schmiedeberg's Archives of Pharmacology (2026)
2. Neuroprotective Effects of Sodium Nitroprusside on Ckd-Induced Cognitive Dysfunction in Rats: Role of Cbs and Nrf2/Ho-1 Pathway, NeuroMolecular Medicine (2025)
3. Hydrogen Sulfide Upregulates Hypoxia Inducible Factors and Erythropoietin Production in Chronic Kidney Disease Induced by 5/6 Nephrectomized Rats, Molecular Biology Reports (2024)
4. Pag Masked Protective Physical Exercise-Induced High H2s Levels in 5/6 Nephrectomized Rats, Iranian Journal of Pharmaceutical Research (2024)
5. Prevention of Glycerol-Induced Acute Kidney Injury by Isoflurane Inhalation in Male Rats, Physiology and Pharmacology (Iran) (2024)
6. A Comparison Between Centrally and Systemically Administered Erythropoietin on Kidney Protection in a Model of Fixed-Volume Hemorrhagic Shock in Male Rats, Molecular Biology Reports (2023)
7. N-Acetyl Cysteine in Combination With Forelimbs Remote Ischemic Preconditioning Improves the Contrast-Induced Nephropathy: An In-Vivo Experimental Study, Physiology and Pharmacology (Iran) (2023)
8. Point-Of-Care Salivary Oxidative and Renal Functional Markers to Assess Kidney Function in Reperfusion-Induced Acute Kidney Injury in Male Rats, Hormone Molecular Biology and Clinical Investigation (2023)
9. The Effect of Tannic Acid on Renal Renin-Angiotensin Signaling Pathway in a Model of Unilateral Ureteral Obstruction in Male Wistar Rats, Naunyn-Schmiedeberg's Archives of Pharmacology (2023)
10. The Effects of Corm3 or Nahs on the Oxidative Stress Caused by Chronic Kidney Disease in Rats: Potential Interaction Between Co and H2s Signaling Pathway, Metabolic Brain Disease (2023)
11. Beneficial Effects of Combination Therapy With Testosterone and Hydrogen Sulfide by Reducing Oxidative Stress and Apoptosis: Rat Experimental Varicocele Model, International Journal of Reproductive BioMedicine (2022)
12. Mesenchymal Stem Cells and Their Conditioned Medium As Potential Therapeutic Strategies in Managing Comorbid Anxiety in Rat Sepsis Induced by Cecal Ligation and Puncture, Iranian Journal of Basic Medical Sciences (2022)
13. Nephroprotection Through Modifying the Apoptotic Tnf-Α/Erk1/2/Bax Signaling Pathway and Oxidative Stress by Long-Term Sodium Hydrosulfide Administration in Ovalbumin-Induced Chronic Asthma, Immunological Investigations (2022)
14. Therapeutic Effects of Corm3 and Nahs in Chronic Kidney Disease Induced Cognitive Impairment Via the Interaction Between Carbon Monoxide and Hydrogen Sulfide on Nrf2/Ho-1 Signaling Pathway in Rats, Chemico-Biological Interactions (2022)
15. Evaluation of the Brain Tissue Oxidative Stress Status During Sepsis After Mesenchymal Stem Cell's Conditioned Medium Administration in Male Rats, Tehran University Medical Journal (2021)
16. Sperm and Testicular Dysfunction During Cecal Ligation and Puncture-Induced Sepsis in Male Rats and Effects of Tannic Acid Through Reducing Testicular Oxidative Stress and Inflammation, Iranian Journal of Basic Medical Sciences (2021)
17. Study on the Critical Roles of Apoptosis in Asthma Disease, Acta Medica Iranica (2021)
18. Adipose-Derived Mesenchymal Stem Cells and Conditioned Medium Attenuate the Memory Retrieval Impairment During Sepsis in Rats, Molecular Neurobiology (2020)
19. Administration of Sodium Hydrosulfide Reduces Remote Organ Injury by an Anti-Oxidant Mechanism in a Rat Model of Varicocele, Iranian Journal of Basic Medical Sciences (2020)
20. An Overview of High-Mobility Group Box 1, a Potent Pro-Inflammatory Cytokine in Asthma, Journal of Basic and Clinical Physiology and Pharmacology (2020)
21. Long-Term Nahs Administration Reduces Oxidative Stress and Apoptosis in a Rat Model of Left-Side Varicocele, Andrologia (2020)
22. Protective Effects of Ascorbic Acid and Calcitriol Combination on Airway Remodelling in Ovalbumin-Induced Chronic Asthma, Pharmaceutical Biology (2020)
23. The Impact of Sex Differences on Renal Protective Effects of Lipopolysaccharide Preconditioning in Septic Shock, Iranian Journal of Medical Sciences (2020)
24. Additional Effects of Erythropoietin Pretreatment, Ischemic Preconditioning, and N-Acetylcysteine Posttreatment in Rat Kidney Reperfusion Injury, Turkish Journal of Medical Sciences (2019)
25. Combination of Ascorbic Acid and Calcitriol Attenuates Chronic Asthma Disease by Reductions in Oxidative Stress and Inflammation, Respiratory physiology & neurobiology (2019)
26. Inducible and Endothelial Nitric Oxide Synthase Distribution and Expression With Hind Limb Per-Conditioning of the Rat Kidney, Archives of Medical Science (2019)
27. Long-Term Exercise Restores Hydrogen Sulfide in the Kidney and Contributes to Exercise Benefits in 5/6 Nephrectomized Rats, Clinical and Experimental Hypertension (2019)
28. Oxidative Stress, Nitric Oxide and Inflammation in the Pathophysiology of Varicocele and the Effect of Hydrogen Sulfide As a Potential Treatment, Physiology and Pharmacology (Iran) (2019)
29. Protective Effects of Celecoxib on Ischemia Reperfusion–Induced Acute Kidney Injury: Comparing Between Male and Female Rats, Iranian Journal of Basic Medical Sciences (2019)
30. Protective Effects of Hydrogen Sulfide on Anxiety in Ovalbumin-Induced Chronic Asthma, Physiology and Pharmacology (Iran) (2019)
31. Nephroprotection Through the Akt/Enos Pathway by Centrally Administered Erythropoietin in a Rat Model of Fixed-Volume Hemorrhage, Life Sciences (2018)
32. Opioid Use Disorder Induces Oxidative Stress and Inflammation: The Attenuating Effect of Methadone Maintenance Treatment, Iranian Journal of Psychiatry (2018)
33. Protective Effects of Hydrogen Sulfide on Chronic Kidney Disease by Reducing Oxidative Stress, Inflammation and Apoptosis, EXCLI Journal (2018)
34. Different Dose-Dependent Effects of Hydrogen Sulfide on Ischemiareperfusion Induced Acute Kidney Injury in Rats, Tehran University Medical Journal (2017)
35. Erythropoietin Attenuates Experimental Haemorrhagic Shock-Induced Renal Damage Through an Inos- Dependent Mechanism in Male Wistar Rats, Injury (2017)
36. Impact of Opioids on Oxidative Status and Related Signaling Pathways: An Integrated View, Journal of Opioid Management (2017)
37. Involvement of Neuronal Pathways in the Protective Effects of Hindlimb Perconditioning During Renal Ischemia, Experimental and Therapeutic Medicine (2017)
38. Renal Tissue Pro-Inflammatory Gene Expression Is Reduced by Erythropoietin in Rats Subjected to Hemorrhagic Shock, Journal of Nephropathology (2017)
39. Up-Regulation of Nitric Oxide Synthases by Erythropoietin Alone or in Conjunction With Ischemic Preconditioning in Ischemia Reperfusion Injury of Rat Kidneys, General Physiology and Biophysics (2017)
40. Administration of Hydrogen Sulfide Protects Ischemia Reperfusion-Induced Acute Kidney Injury by Reducing the Oxidative Stress, Irish Journal of Medical Science (2016)
41. Evaluation of Renal-Hepatic Functional Indices and Blood Pressure Based on the Progress of Time in a Rat Model of Chronic Kidney Disease, Nephro-Urology Monthly (2016)
42. Hind Limb Perconditioning Renoprotection by Modulation of Inflammatory Cytokines After Renal Ischemia/Reperfusion, Renal Failure (2016)
43. Ameliorative Effect of Recombinant Human Erythropoietin and Ischemic Preconditioning on Renal Ischemia Reperfusion Injury in Rats, Nephro-Urology Monthly (2015)
44. Angiotensin Ii in Paraventricular Nucleus Contributes to Sympathoexcitation in Renal Ischemia-Reperfusion Injury by At1 Receptor and Oxidative Stress, Journal of Surgical Research (2015)
45. Free Radical Scavengers Improve Liver Function But Not Morphological Changes Induced by Reperfusion Injury, Journal of Investigative Surgery (2015)
46. Postconditioning Is Protective in Renal Reperfusion Injury Only in Male Rats. a Gender Difference Study, Acta Physiologica Hungarica (2015)
47. Reduction of Hemorrhagic Shock–Induced Acute Kidney Injury by Lower Limb Ischemic Preconditioning in Rats, Physiology and Pharmacology (2015)