Tehran University of Medical Sciences

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Faculty Members have conducted research related to the In Silico Investigation of New Binding Pocket for Mitogen Activated Kinase Kinase (Mek): Development of New Promising Inhibitors
Vahid Haghpanah
Vahid Haghpanah

Associate Professor of Molecular Medicine

Endocrinology and Metabolism Research Center

Endocrinology and Metabolism Research Institute

Tehran University of Medical Sciences

All Documents
1. Continued Rise in the Incidence of Thyroid Cancer in Iran: True Increase or Overdiagnosis?, Journal of Diabetes and Metabolic Disorders (2025)
2. Exploring the Inhibitory Potential of Xanthohumol on Mek1/2: A Molecular Docking and Dynamics Simulation Investigation, Research in Pharmaceutical Sciences (2024)
3. Decoding the Expression Pattern of Muc3a in Gastric Adenocarcinoma: Unveiling the Key to Successful Immunotherapy, Expert Opinion on Therapeutic Targets (2023)
4. Design and Implementation of a National Quality Registry of Thyroid Cancer in Iran: Study Protocol, Journal of Diabetes and Metabolic Disorders (2023)
5. Design, Synthesis, and Cytotoxic Evaluation of Quinazoline Derivatives Bearing Triazole-Acetamides, Heliyon (2023)
6. Illuminating the Role of Lncrnas Ror and Malat1 in Cancer Stemness State of Anaplastic Thyroid Cancer: An Exploratory Study, Non-coding RNA Research (2023)
7. Management Goal Achievements of Diabetes Care in Iran: Study Profile and Main Findings of Diacare Survey, Journal of Diabetes and Metabolic Disorders (2023)
8. Prevalence of Thyroid Dysfunction Among Iranian Older Adults: A Cross-Sectional Study, Scientific Reports (2023)
9. The Effects of Abemaciclib on Cell Cycle and Apoptosis Regulation in Anaplastic Thyroid Cancer Cells, Molecular Biology Reports (2023)
10. Xanthohumol Hinders Invasion and Cell Cycle Progression in Cancer Cells Through Targeting Mmp2, Mmp9, Fak and P53 Genes in Three-Dimensional Breast and Lung Cancer Cells Culture, Cancer Cell International (2023)
11. Bi-847325, a Selective Dual Mek and Aurora Kinases Inhibitor, Reduces Aggressive Behavior of Anaplastic Thyroid Carcinoma on an in Vitro Three-Dimensional Culture, Cancer Cell International (2022)
12. Development of a Multiepitope Vaccine Against Sars-Cov-2: Immunoinformatics Study, JMIR Bioinformatics and Biotechnology (2022)
13. Molecular Evidence Reveals Thyrotropin Intervention Enhances the Risk of Developing Radioiodine-Refractory Differentiated Thyroid Carcinoma, Cancer Cell International (2022)
14. Recent Advances in Gene Therapy-Based Cancer Monotherapy and Synergistic Bimodal Therapy Using Upconversion Nanoparticles: Structural and Biological Aspects, Biomedicine and Pharmacotherapy (2022)
15. A Systematic Review on Thyroid Organoid Models: Time-Trend and Its Achievements, American Journal of Physiology - Endocrinology and Metabolism (2021)
16. Alginate-Based 3D Cell Culture Technique to Evaluate the Half-Maximal Inhibitory Concentration: An in Vitro Model of Anticancer Drug Study for Anaplastic Thyroid Carcinoma, Thyroid Research (2021)
17. Determination of Ultrasonographic Characteristics of Thyroid Nodules for Thyroid Cancer Prediction, Iranian Journal of Diabetes and Metabolism (2021)
18. Establishment of Biobank Facility at Endocrinology and Metabolism Research Institute of Iran: Experiences, Challenges, and Future Outlook, Journal of Diabetes and Metabolic Disorders (2021)
19. Global, Regional, and National Burden and Quality of Care Index (Qci) of Thyroid Cancer: A Systematic Analysis of the Global Burden of Disease Study 1990–2017, Cancer Medicine (2021)
20. Thyroid Cancer Research at Endocrinology and Metabolism Research Institute (Emri): A Report of Scientific Activities Between 2005 and 2020, Journal of Diabetes and Metabolic Disorders (2021)
21. An Estimation of Clinical Hyperthyroidism Prevalence in the National and Sub-National Levels in Iran Using Claims Data, Iranian Journal of Diabetes and Metabolism (2020)
22. Bioinformatic Study on Effect of Xanthohumol As Bioactive Compound of Hop in the Inhibition of the Mapk/Erk Pathway in Thyroid Cancer, Iranian Journal of Diabetes and Metabolism (2020)
23. Biosafety Guidelines for Covid-19 Specimens in Biobanks, Biopreservation and Biobanking (2020)
24. Gut Microbiome and Radioiodine-Refractory Papillary Thyroid Carcinoma Pathophysiology, Trends in Endocrinology and Metabolism (2020)
25. Investigation of Promoter Methylation of Fscn1 Gene and Fscn1 Protein Expression in Differentiated Thyroid Carcinomas, Molecular Biology Reports (2020)
26. Molecular Mechanisms of Long Non-Coding Rnas in Anaplastic Thyroid Cancer: A Systematic Review, Cancer Cell International (2020)
27. Network Analysis Reveals Essential Proteins That Regulate Sodium-Iodide Symporter Expression in Anaplastic Thyroid Carcinoma, Scientific Reports (2020)
28. Inappropriate Modeling of Chronic and Complex Disorders: How to Reconsider the Approach in the Context of Predictive, Preventive and Personalized Medicine, and Translational Medicine, EPMA Journal (2019)
29. The Role of Atp-Binding Cassette Transporters in the Chemoresistance of Anaplastic Thyroid Cancer: A Systematic Review, Endocrinology (2019)
30. Transcript-Level Regulation of Malat1-Mediated Cell Cycle and Apoptosis Genes Using Dual Mek/Aurora Kinase Inhibitor “Bi-847325” on Anaplastic Thyroid Carcinoma, DARU# Journal of Pharmaceutical Sciences (2019)
31. Cellulose Acetate Electrospun Nanofibers for Drug Delivery Systems: Applications and Recent Advances, Carbohydrate Polymers (2018)
32. Precision Medicine Approach to Anaplastic Thyroid Cancer: Advances in Targeted Drug Therapy Based on Specific Signaling Pathways, Acta Medica Iranica (2017)
33. Smart Article: Application of Intelligent Platforms in Next Generation Biomedical Publications, Journal of Diabetes and Metabolic Disorders (2017)
34. 7Sk Small Nuclear Rna Transcription Level Down-Regulates in Human Tumors and Stem Cells, Medical Oncology (2016)
35. Antisense-Mir-21 Enhances Differentiation/Apoptosis and Reduces Cancer Stemness State on Anaplastic Thyroid Cancer, Tumor Biology (2016)
36. Cancer Stem-Like Cell Behavior in Anaplastic Thyroid Cancer: A Challenging Dilemma, Life Sciences (2016)
37. Clothes Do Not Make the Man: Wellfavored Figures Are Game-Changers in the Biomedical Publication, Journal of Korean Medical Science (2015)
38. Efficacy of the Hatching Event in Assessing the Embryo Toxicity of the Nano-Sized Tio2 Particles in Zebrafish: A Comparison Between Two Different Classes of Hatching-Derived Variables, Ecotoxicology and Environmental Safety (2015)
39. Expression of the Pituitary Tumor Transforming Gene (Pttg1) in Pheochromocytoma As a Potential Marker for Distinguishing Benign Versus Malignant Tumors, Acta Medica Iranica (2015)