Tehran University of Medical Sciences

Science Communicator Platform

Faculty Members have conducted research related to the Design, Synthesis, Molecular Docking, and Preclinical Evaluation of a New Radiolabeled Peg3-Linked Fapi Derivative for Fibroblast Activation Protein Targeting
Safura Jokar

Assistant Professor of Nuclear Pharmacy

Department Nuclear Pharmacy

School of Pharmacy

Tehran University of Medical Sciences

All Documents
1. Design and Evaluation of a Chalcone-Based Dimeric Scaffold Targeting Amyloid-Beta Plaques for Early Detection of Alzheimer’S Disease: Synthesis, Radiolabeling, in Vivo Studies, and Integrated Molecular Docking and Dynamics Simulation, Advanced Pharmaceutical Bulletin (2026)
2. Design, Synthesis, Molecular Docking, and Preclinical Evaluation of a New Radiolabeled Peg3-Linked Fapi Derivative for Fibroblast Activation Protein Targeting, Iranian Journal of Pharmaceutical Research (2026)
3. Synthesis, Radiolabeling, and Biodistribution Evaluation of Novel Hyperbranched Polyglycerols-Based Radiotracers for Targeting Psma in Prostate Cancer, Iranian Journal of Basic Medical Sciences (2026)
4. 99Mtc-Snw-1 Nanoparticle Labeling and Its Biodistribution/Pathological Evaluations, Journal of Labelled Compounds and Radiopharmaceuticals (2025)
5. Design of Chiral 2-Oxazoline-Based Amino Acid Bioconjugates As Anticancer Agents: Synthesis, in Vitro Anticancer Activity, Admet Prediction With Molecular Docking and Molecular Dynamic Simulation Insights, Archives of Biochemistry and Biophysics (2025)
6. Design of a New 99M99mtc-Radiolabeled Cyclo-Peptide As Promising Molecular Imaging Agent of Cxcr4 Receptor: Molecular Docking, Synthesis, Radiolabeling, and Biological Evaluation, Current Radiopharmaceuticals (2024)
7. Radiolabeling of the Mutant Form of Anti-Plgf Nanobody By99m Tc-Tricarbonyl, Iranian Journal of Pharmaceutical Research (2024)
8. Recent Clinical Implications of Fapi Imaging and Therapy, Clinical Nuclear Medicine (2024)
9. Self-Assembled Peptide/Polymer Hybrid Nanoplatform for Cancer Immunostimulating Therapies, Drug Delivery and Translational Research (2024)
10. Synthesis, Biological Evaluation, and in Silico Study of Novel Coumarin-Quinazoline Analogs As Potential Anti-Angiogenesis Agents, Results in Chemistry (2024)
11. X-Ray-Based Cancer Diagnosis and Treatment Methods, Electromagnetic Waves-Based Cancer Diagnosis and Therapy: Principles and Applications of Nanomaterials (2023)
12. Targeting Caveolin-1 and Claudin-5 With Ay9944, Improve Blood–Brain Barrier Permeability; Computational Simulation and Experimental Study, Cellular and Molecular Neurobiology (2022)
13. The Footprint of Exosomes in the Radiation-Induced Bystander Effects, Bioengineering (2022)
14. Design of Peptide-Based Inhibitor Agent Against Amyloid-Β Aggregation: Molecular Docking, Synthesis and in Vitro Evaluation, Bioorganic Chemistry (2020)
15. Design, Preparation and Biological Evaluation of a 177Lu-Labeled Somatostatin Receptor Antagonist for Targeted Therapy of Neuroendocrine Tumors, Bioorganic Chemistry (2020)
16. Preclinical Study of a New 177Lu-Labeled Somatostatin Receptor Antagonist in Ht-29 Human Colorectal Cancer Cells, Asia Oceania Journal of Nuclear Medicine and Biology (2020)
17. Synthesis, Biological Evaluation and Preclinical Study of a Novel 99Mtc-Peptide: A Targeting Probe of Amyloid-Β Plaques As a Possible Diagnostic Agent for Alzheimer's Disease, Bioorganic Chemistry (2020)
18. Recent Advances in the Design and Applications of Amyloid-Β Peptide Aggregation Inhibitors for Alzheimer’S Disease Therapy, Biophysical Reviews (2019)