Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
X-Ray-Based Cancer Diagnosis and Treatment Methods Publisher



Jokar S1, 2 ; Khazaei S3 ; Behnammanesh H4, 5 ; Laranjo M2, 6, 7 ; Beiki D8 ; Botelho MF2, 6, 7
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Nuclear Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Institute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, Coimbra, Portugal
  3. 3. Department of Pharmaceutical Biomaterials, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Department of Pharmaceutical Chemistry and Radiopharmacy, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  6. 6. Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal
  7. 7. Clinical and Academic Centre of Coimbra (CACC), Coimbra, Portugal
  8. 8. Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Electromagnetic Waves-Based Cancer Diagnosis and Therapy: Principles and Applications of Nanomaterials Published:2023


Abstract

X-rays are one of the most widely used electromagnetic waves in modern medicine. Iodinated-based contrast agents are commonly used in X-ray imaging techniques. Despite the rich information provided by contrast agent–based X-ray imaging, these agents are not optimal because of serious challenges such as short blood circulation, fast clearance, nonspecific biodistribution, and renal toxicity. Hence, nontoxic contrast agents with long-lasting circulation time are still a research gap that is being widely investigated. Nanotechnology has gained attention as a means to surpass the limitations of conventional contrast agents. Nanostructures, with accurate design and good properties control, can become interesting imaging contrast agents. Additionally, nanoparticle research and development also have resulted in novel radiosensitizers and radioprotective agents for radiotherapy. This chapter provides a comprehensive overview of the basics of X-rays and the types of X-ray-based imaging modalities and radiotherapy. Subsequently, we highlight the most recent advances and future perspectives in the application of nanotechnology in X-ray-based imaging methods and radiotherapy. © 2023 Elsevier Inc. All rights reserved.
Related Docs
View other Related Docs
1. Application of Nano-Radiosensitizers in Combination Cancer Therapy, Bioengineering and Translational Medicine (2023)
2. Critical Parameters to Translate Gold Nanoparticles As Radiosensitizing Agents Into the Clinic, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology (2023)
3. An Update on Nanoparticle-Based Contrast Agents in Medical Imaging, Artificial Cells# Nanomedicine and Biotechnology (2018)
4. Evaluation of Size, Morphology, Concentration, and Surface Effect of Gold Nanoparticles on X-Ray Attenuation in Computed Tomography, Physica Medica (2018)
5. A Nanotechnology-Based Strategy to Increase the Efficiency of Cancer Diagnosis and Therapy: Folate-Conjugated Gold Nanoparticles, Current Medicinal Chemistry (2017)
6. Solid Silica Nanoparticles: Applications in Molecular Imaging, Contrast Media and Molecular Imaging (2015)
7. Nanotechnology-Assisted Lung Cancer Diagnosis: Biomarkers and Imaging, Journal of Nanoparticle Research (2025)
8. Toxicity, Morphological and Structural Properties of Chitosan-Coated Bi2o3-Bi(Oh)3 Nanoparticles Prepared Via Dc Arc Discharge in Liquid: A Potential Nanoparticle-Based Ct Contrast Agent, Micro and Nano Letters (2019)
Experts (# of related papers)
View all Related Experts
Sharmin Kharrazi (5)
Saeid Sarkar (3)
Other Related Docs
9. High-Performance Spirulina-Bismuth Biohybrids for Enhanced Computed Tomography Imaging, ACS Sustainable Chemistry and Engineering (2020)
10. The Effect of Bismuth Nanoparticles in Kilovoltage and Megavoltage Radiation Therapy Using Magnetic Resonance Imaging Polymer Gel Dosimetry, Radiation Physics and Chemistry (2020)
11. Gold Cluster Encapsulated Liposomes: Theranostic Agent With Stimulus Triggered Release Capability, Medical Oncology (2023)
12. Metal, Metalloid, and Oxide Nanoparticles for Therapeutic and Diagnostic Oncology, Nano Biomedicine and Engineering (2016)
13. The Radioprotective Effect of Combination of Melatonin and Metformin on Rat Duodenum Damage Induced by Ionizing Radiation: A Histological Study, Advanced Biomedical Research (2019)
14. Cancer Nanomedicine: Special Focus on Cancer Immunotherapy, Cancer Immunology: Bench to Bedside Immunotherapy of Cancers# Second Edition (2020)
15. Harnessing the Cancer Radiation Therapy by Lanthanide-Doped Zinc Oxide Based Theranostic Nanoparticles, ACS Applied Materials and Interfaces (2016)
16. Effects of Noncoding Rnas in Radiotherapy Response in Breast Cancer: A Systematic Review, Cell Cycle (2022)
17. Current Perspective on Theranostic Gold Nanoparticles: Synthesis and Biomedical Applications, Nanomedicine Journal (2023)
18. A Review of Recent Developments of Metal–Organic Frameworks As Combined Biomedical Platforms Over the Past Decade, Advances in Colloid and Interface Science (2023)
19. Folate-Conjugated Gold Nanoparticle As a New Nanoplatform for Targeted Cancer Therapy, Journal of Cancer Research and Clinical Oncology (2016)
20. Modulation of Apoptosis by Melatonin for Improving Cancer Treatment Efficiency: An Updated Review, Life Sciences (2019)
21. Pharmacokinetics and Biodistribution Studies of [99Mtc]-Labeled Zif-8 Nanoparticles to Pave the Way for Image-Guided Drug Delivery and Theranostics, Journal of Drug Delivery Science and Technology (2023)
22. Recent Advances in Glioblastoma Multiforme Therapy: A Focus on Autophagy Regulation, Biomedicine and Pharmacotherapy (2022)
23. Folic Acid-Cysteamine Modified Gold Nanoparticle As a Nanoprobe for Targeted Computed Tomography Imaging of Cancer Cells, Materials Science and Engineering C (2018)
24. Monte Carlo Simulation and Analytical Calculation Methods to Investigate the Potential of Nanoparticles for Intrabeam® Iort Machine, Nanomedicine: Nanotechnology# Biology# and Medicine (2020)
25. The Role and Mechanisms of Zinc Oxide Nanoparticles in the Improvement of the Radiosensitivity of Lung Cancer Cells in Clinically Relevant Megavoltage Radiation Energies In-Vitro, Nanomedicine Journal (2019)
26. Investigation of the Dose Enhancement Effect of Spherical Bismuth Oxide Nanoparticles in External Beam Radiotherapy, Nanomedicine Research Journal (2020)