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The Effects of Bitter Melon (Momordica Charantia) on Anthropometric Indices in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Publisher Pubmed



Zou Y1 ; Zou W2 ; Jahangir M3 ; Haedi A4
Authors
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Authors Affiliations
  1. 1. Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Jiangxi Province, Nanchang, 330000, China
  2. 2. Department of General Surgery, The Third Hospital of Nanchang, Jiangxi Province, Nanchang, 330000, China
  3. 3. Department of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Faculty of Nutrition and Food Science, Tehran University of Medical Sciences, Tehran, Iran

Source: Prostaglandins and Other Lipid Mediators Published:2024


Abstract

There is controversial data on the impacts of bitter melon (Momordica charantia) supplementations on anthropometric indices. Thus, we aimed to clarify this role of bitter melon through a systematic review, and meta-analysis of the trials. All clinical trials conducted on the impact of bitter melon on anthropometric indices were published until August 2023 in PubMed, Web of Sciences, Scopus, Embase, and Cochrane Library web databases included. Overall, 10 studies with 448 individuals were included in the meta-analysis. Meta-analysis of 10 trials with 448 participants revealed no significant reductions in body weight (BW) (WMD: 0.04 Kg; 95 %CI: −0.16–0.25; P =0.651), body mass index (BMI) (WMD: −0.18 kg/m2; 95 %CI: −0.43–0.07; P =0.171), waist circumference (WC) (WMD: −0.95 cm; 95 % CI: −3.05–1.16; p =0.372), and percentage of body fat (PBF) (WMD: −0.99; 95 % CI: −2.33–0.35; p =0.141) following bitter melon supplementation. There was no significant impact of bitter melon supplementation on BW, BMI, WC, and PBF. More large-scale and high-quality RCTs are necessary to confirm these results. © 2024 Elsevier Inc.
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