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Bone Structure and Turnover in Postmenopausal Women With Type 2 Diabetes Mellitus Publisher Pubmed



Razi F1 ; Esmaili M2 ; Esfahani EN1 ; Yaghmaei P2 ; Qorbani M3, 4 ; Mohammadi Z5 ; Keshtkar A6 ; Khashayar P5, 7 ; Larijani B8
Authors
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Authors Affiliations
  1. 1. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
  3. 3. Department of Community Medicine, Alborz University of Medical Sciences, Karaj, Iran
  4. 4. Department of Epidemiology and Biostatistics, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Health Sciences Education Development, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Center for Microsystems Technology, Imec and Universiteit Gent, Zwinjaarde, Belgium
  8. 8. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Menopause Published:2016


Abstract

Objective: Considering the high prevalence of diabetes and osteoporosis in Iranians, the current research was conducted to study the correlation between these two diseases in a group of postmenopausal women. Methods: The present study was conducted on postmenopausal women recruited in the third phase of the Iranian Multi-centric Osteoporosis Study. They were divided into two groups (diabetic and nondiabetic) based on their diabetes history and laboratory results. The serum levels of bone markers and bone mineral density values were compared between the two groups. Results: A total of 110 postmenopausal women were included. Although bone mineral density values were nonsignificantly higher in diabetic postmenopausal women, there was no considerable difference between the prevalence of osteoporosis or serum levels of bone markers in the two groups. Conclusions: There is no difference in bone mass values or bone turnover process between Iranian postmenopausal women with or without diabetes. © 2016 The North American Menopause Society.