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Synthesis of Novel 1,2,3-Triazole-Dihydro[3,2-C[Chromenones As Acetylcholinesterase Inhibitors Publisher



Saeedi M1, 2 ; Ansari S3 ; Mahdavi M3 ; Sabourian R2 ; Akbarzadeh T2, 3 ; Foroumadi A3 ; Shafiee A3
Authors
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Authors Affiliations
  1. 1. Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Synthetic Communications Published:2015


Abstract

A novel series of 1,2,3-triazole-dihydro[3,2-c]chromenone derivatives were synthesized through an efficient three-step reaction starting from 4-hydroxybenzaldehyde. All the newly synthesized compounds were characterized by infrared and NMR spectroscopy as well as elemental analysis and evaluated for their acetylcholinesterase inhibitory activity. © 2015 Taylor and Francis Group, LLC.
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