Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma

Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma Publisher Pubmed

Mohebbi E^{1, 2} ; Hadji M^{1, 3} ; Rashidian H¹ ; Rezaianzadeh A⁴ ; Marzban M^{5, 6} ; Haghdoost AA⁷ ; Naghibzadeh Tahami A⁷ ; Moradi A⁸ ; Gholipour M⁸ ; Najafi F^{9, 10} ; Safarifaramani R¹¹ ; Alizadehnavaei R¹² ; Ansarimoghaddam A¹³ ; Bakhshi M¹³ Show All Authors

Mohebbi E^{1, 2}
Hadji M^{1, 3}
Rashidian H¹
Rezaianzadeh A⁴
Marzban M^{5, 6}
Haghdoost AA⁷
Naghibzadeh Tahami A⁷
Moradi A⁸
Gholipour M⁸
Najafi F^{9, 10}
Safarifaramani R¹¹
Alizadehnavaei R¹²
Ansarimoghaddam A¹³
Bakhshi M¹³
Nejatizadeh A^{14, 15}
Mahmoudi M¹⁶
Shahidsales S¹⁷
Ahmadisimab S¹⁷
Arabi Mianroodi AA¹⁸
Seyyedsalehi MS¹
Hosseini B^{1, 19}
Peyghambari V¹
Shirkhoda M¹
Shirkoohi R¹
Ebrahimi E¹
Manifar S¹
Mohagheghi MA¹
Rozek L^{20, 21}
Brennan P²²
Poustchi H²³
Etemadi A^{23, 24}
Pukkala E^{3, 25}
Schuz J²⁶
Malekzadeh R²³
Weiderpass E²²
Rahimimovaghar A²⁷
Boffetta P^{28, 29}
Kamanagar F³⁰
Zendehdel K¹

Show Affiliations

1. Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran
2. Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran
3. Health Science Unit, Faculty of Social Sciences, Tampere University, Tampere, Finland
4. Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
5. School of Public Health, Department of Epidemiology and Biostatistics, Bushehr University of Medical Sciences, Bushehr, Iran
6. The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, The Persian Gulf Department of Aging Health Research, Bushehr University of Medical Sciences, Bushehr, Iran
7. Health Services Management Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
8. Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran
9. Research Center for Environmental Determinants of Health, Institute of Health, Kermanshah Medical Sciences University, Kermanshah, Iran
10. Social Development and Health Promotion Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
11. Research Center for Environmental Determinants of Health, Research Institute for Health, Kermanshah University of Medical Sciences, Kermanshah, Iran
12. Gastrointestinal Cancer Research Center, Non-communicable diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran
13. Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
14. Cardiovascular Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
15. Molecular Medicine Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
16. Hormozgan University of Medical Sciences, Bandar Abbas, Iran
17. Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
18. Department of Otorhinolaryngology Head and Neck Surgery, Shafa Hospital, Kerman University of Medical Sciences, Kerman, Iran
19. International Agency for Research on Cancer (IARC), Lyon, France
20. Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, United States
21. Department of Otolaryngology, University of Michigan, Ann Arbor, MI, United States
22. International Agency for Research on Cancer (IARC/WHO), Lyon, France
23. Digestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
24. Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States
25. Finnish Cancer Registry, Helsinki, Finland
26. Section of Environment and Radiation, International Agency for Research on Cancer (IARC), Lyon, France
27. Iranian National Center for Addiction Studies (INCAS), Tehran University of Medical Sciences, Tehran, Iran
28. Stony Brook Cancer Center, Stony Brook University, Stony Brook, NY, United States
29. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
30. Department of Biology, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, MD, United States

Source: International Journal of Cancer Published:2021

Abstract

Scant evidence exists to support the association of opium use with head and neck cancer, limited to the larynx and oral cavity. In a multicenter case-control study—Iran Opium and Cancer study, we recruited 633 cases of head and neck squamous cell carcinoma (HNSCC) (254 lip and oral cavity, 54 pharynx, 327 larynx and 28 other subsites within the head and neck) and 3065 frequency-matched controls from April 2016 to April 2019. Odds ratios (ORs) for opium use and 95% confidence intervals (95% CIs) were obtained using mixed-effects logistic regression because of heterogeneity among centers. The adjusted OR (95% CI) for regular opium use was 3.76 (2.96-4.79) for all HNSCC combined. Strong dose-response effects were observed by frequency or amount of use, and duration of use. Regular opium uses significantly increased the risk of HNSCC of the pharynx, larynx and other subsites within the head and neck with OR (95% CI) of 2.90 (1.40-6.02), 6.55 (4.69-9.13) and 5.95 (2.41-14.71), respectively. The observed associations were significant even among never tobacco smokers (including cigarette and water-pipe smoking). Moreover, by the multiplicative interaction scale, the effect of opium use could be varied by cigarette smoking on HNSCC, 8.16 (6.20-10.74). For the first time, the current study showed opium users have an increased risk of several anatomic subsites of HNSCC. © 2020 UICC

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Reza Malekzadeh (27)

Hossein Poustchi (20)

Style	Citing Format
MLA	Mohebbi E, et al.. "Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma." International Journal of Cancer, vol. 148, no. 5, 2021, pp. 1066-1076.
APA	Mohebbi E, Hadji M, Rashidian H, Rezaianzadeh A, Marzban M, Haghdoost AA, Naghibzadeh Tahami A, Moradi A, Gholipour M, Najafi F, Safarifaramani R, Alizadehnavaei R, Ansarimoghaddam A, Bakhshi M, Nejatizadeh A, Mahmoudi M, Shahidsales S, Ahmadisimab S, Arabi Mianroodi AA, ... Zendehdel K (2021). Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma. International Journal of Cancer, 148(5), 1066-1076.
Chicago	Mohebbi E, Hadji M, Rashidian H, Rezaianzadeh A, Marzban M, Haghdoost AA, Naghibzadeh Tahami A, et al.. "Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma." International Journal of Cancer 148, no. 5 (2021): 1066-1076.
Harvard	Mohebbi E et al. (2021) 'Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma', International Journal of Cancer, 148(5), pp. 1066-1076.
Vancouver	Mohebbi E, Hadji M, Rashidian H, Rezaianzadeh A, Marzban M, Haghdoost AA, et al.. Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma. International Journal of Cancer. 2021;148(5):1066-1076.
BibTex	@article{ author = {Mohebbi E and Hadji M and Rashidian H and Rezaianzadeh A and Marzban M and Haghdoost AA and Naghibzadeh Tahami A and Moradi A and Gholipour M and Najafi F and Safarifaramani R and Alizadehnavaei R and Ansarimoghaddam A and Bakhshi M and Nejatizadeh A and Mahmoudi M and Shahidsales S and Ahmadisimab S and Arabi Mianroodi AA and Seyyedsalehi MS and Hosseini B and Peyghambari V and Shirkhoda M and Shirkoohi R and Ebrahimi E and Manifar S and Mohagheghi MA and Rozek L and Brennan P and Poustchi H and Etemadi A and Pukkala E and Schuz J and Malekzadeh R and Weiderpass E and Rahimimovaghar A and Boffetta P and Kamanagar F and Zendehdel K}, title = {Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma}, journal = {International Journal of Cancer}, volume = {148}, number = {5}, pages = {1066-1076}, year = {2021} }
RIS	TY - JOUR AU - Mohebbi E AU - Hadji M AU - Rashidian H AU - Rezaianzadeh A AU - Marzban M AU - Haghdoost AA AU - Naghibzadeh Tahami A AU - Moradi A AU - Gholipour M AU - Najafi F AU - Safarifaramani R AU - Alizadehnavaei R AU - Ansarimoghaddam A AU - Bakhshi M AU - Nejatizadeh A AU - Mahmoudi M AU - Shahidsales S AU - Ahmadisimab S AU - Arabi Mianroodi AA AU - Seyyedsalehi MS AU - Hosseini B AU - Peyghambari V AU - Shirkhoda M AU - Shirkoohi R AU - Ebrahimi E AU - Manifar S AU - Mohagheghi MA AU - Rozek L AU - Brennan P AU - Poustchi H AU - Etemadi A AU - Pukkala E AU - Schuz J AU - Malekzadeh R AU - Weiderpass E AU - Rahimimovaghar A AU - Boffetta P AU - Kamanagar F AU - Zendehdel K TI - Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma JO - International Journal of Cancer VL - 148 IS - 5 SP - 1066 EP - 1076 PY - 2021 ER -

Style

Citing Format

MLA

Mohebbi E, et al.. "Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma." International Journal of Cancer, vol. 148, no. 5, 2021, pp. 1066-1076.

APA

Mohebbi E, Hadji M, Rashidian H, Rezaianzadeh A, Marzban M, Haghdoost AA, Naghibzadeh Tahami A, Moradi A, Gholipour M, Najafi F, Safarifaramani R, Alizadehnavaei R, Ansarimoghaddam A, Bakhshi M, Nejatizadeh A, Mahmoudi M, Shahidsales S, Ahmadisimab S, Arabi Mianroodi AA, ... Zendehdel K (2021). Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma. International Journal of Cancer, 148(5), 1066-1076.

Chicago

Mohebbi E, Hadji M, Rashidian H, Rezaianzadeh A, Marzban M, Haghdoost AA, Naghibzadeh Tahami A, et al.. "Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma." International Journal of Cancer 148, no. 5 (2021): 1066-1076.

Harvard

Mohebbi E et al. (2021) 'Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma', International Journal of Cancer, 148(5), pp. 1066-1076.

Vancouver

Mohebbi E, Hadji M, Rashidian H, Rezaianzadeh A, Marzban M, Haghdoost AA, et al.. Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma. International Journal of Cancer. 2021;148(5):1066-1076.

BibTex

@article{ author = {Mohebbi E and Hadji M and Rashidian H and Rezaianzadeh A and Marzban M and Haghdoost AA and Naghibzadeh Tahami A and Moradi A and Gholipour M and Najafi F and Safarifaramani R and Alizadehnavaei R and Ansarimoghaddam A and Bakhshi M and Nejatizadeh A and Mahmoudi M and Shahidsales S and Ahmadisimab S and Arabi Mianroodi AA and Seyyedsalehi MS and Hosseini B and Peyghambari V and Shirkhoda M and Shirkoohi R and Ebrahimi E and Manifar S and Mohagheghi MA and Rozek L and Brennan P and Poustchi H and Etemadi A and Pukkala E and Schuz J and Malekzadeh R and Weiderpass E and Rahimimovaghar A and Boffetta P and Kamanagar F and Zendehdel K}, title = {Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma}, journal = {International Journal of Cancer}, volume = {148}, number = {5}, pages = {1066-1076}, year = {2021} }

RIS

TY - JOUR
AU - Mohebbi E
AU - Hadji M
AU - Rashidian H
AU - Rezaianzadeh A
AU - Marzban M
AU - Haghdoost AA
AU - Naghibzadeh Tahami A
AU - Moradi A
AU - Gholipour M
AU - Najafi F
AU - Safarifaramani R
AU - Alizadehnavaei R
AU - Ansarimoghaddam A
AU - Bakhshi M
AU - Nejatizadeh A
AU - Mahmoudi M
AU - Shahidsales S
AU - Ahmadisimab S
AU - Arabi Mianroodi AA
AU - Seyyedsalehi MS
AU - Hosseini B
AU - Peyghambari V
AU - Shirkhoda M
AU - Shirkoohi R
AU - Ebrahimi E
AU - Manifar S
AU - Mohagheghi MA
AU - Rozek L
AU - Brennan P
AU - Poustchi H
AU - Etemadi A
AU - Pukkala E
AU - Schuz J
AU - Malekzadeh R
AU - Weiderpass E
AU - Rahimimovaghar A
AU - Boffetta P
AU - Kamanagar F
AU - Zendehdel K
TI - Opium Use and the Risk of Head and Neck Squamous Cell Carcinoma
JO - International Journal of Cancer
VL - 148
IS - 5
SP - 1066
EP - 1076
PY - 2021
ER -

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