Immunopathology and Immunotherapy of Hodgkin Lymphoma Publisher



Ebadi M¹ ; Keshavarzfathi M^{2, 3} ; Zeng Y⁴ ; Gkotzamanidou M⁵ ; Rezaei N^{6, 7, 8}
Source: Cancer Immunology: Cancer Immunotherapy for Organ-Specific Tumors Published:2020

Abstract

Immunotherapy has led to promising results in the treatment of malignancies in recent decades. In view of the suboptimal results obtained by applying other treatment modalities in the treatment of Hodgkin lymphoma (HL), attention has been drawn to immunotherapy as an efficient alternative or complement therapy. This chapter seeks to discuss a wide spectrum of immunotherapeutic approaches, from initial monoclonal antibodies to novel techniques developed in recent years, which are still at their infancy. Since correct understanding of the underlying immunopathology seems inevitable in efficient immunotherapy and development of future techniques, a brief description with the emphasis on suitable targets for immunotherapy is given before discussing various immunotherapies. © Springer Nature Switzerland AG 2020. All rights reserved.