The Inverse Association of Body Adiposity Index and Bone Health in the Older Adults: A Report From a Developing Country Publisher Pubmed



Djafari F¹ ; Eslahi M² ; Zandi N³ ; Pazoki B³ ; Reza Amini M¹ ; Shabbidar S¹ Show Affiliations
Source: International Journal of Clinical Practice Published:2021

Abstract

The ageing process influences body composition and could be related to bone health. The current study was set out to evaluate the association between body adiposity index (BAI) and bone health in older adults. This is a cross-sectional study performed on 178 elderly persons (51 men and 127 women) with a mean age of 67.04 (range: 60-83) who was referred to the determined 25 health centres in Tehran. The anthropometric measurements were done. Further, serum 25-hydroxy vitamin D (25(OH)D), parathormone (PTH), high-sensitivity C-reactive protein (hs-CRP), osteocalcin and urine C-terminal telopeptide I (CTX-I) were collected. The mean of body mass index (P <.001), body weight (P =.002), body fat (P <.001), waist circumference (P <.001), hip circumference (P <.001), urine CTX-I concentration (P =.011), 25(OH)D (P =.030), was higher in the highest BAI category in comparison with the lowest one. BAI was negatively correlated with urine CTX-I concentration (r=−0.165, P =.028). Moreover, linear regression showed an inverse association between BAI with urine CTX-I (β = −0.165, P =.025) and 25(OH)D (β = −0.039, P =.029). Moreover, the percentage of body fat was positively associated with serum hs-CRP (β = 0.026, P =.002). Our study showed a significant inverse association between BAI with urinary CTX-I which shows the effect of obesity on bone health. This study suggests that more clinical and prospective studies for monitoring body fat may have some favourable impacts on bone health. © 2021 John Wiley & Sons Ltd