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Mean Cycloplegic Refractive Error in Emmetropic Adults – the Tehran Eye Study Publisher



Rozema JJ1, 2, 3 ; Iribarren R4 ; Hashemi H5 ; Khabazkhoob M6 ; Fotouhi A7
Authors
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Authors Affiliations
  1. 1. Visual Optics Lab Antwerp (VOLANTIS), University of Antwerp, Antwerp, Belgium
  2. 2. Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium
  3. 3. Institute for Medical Informatics, Statistics, and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany
  4. 4. Drs. Iribarren Eye Consultants, Buenos Aires, Argentina
  5. 5. Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran
  6. 6. Department of Basic Sciences, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  7. 7. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Optometry Published:2024


Abstract

Purpose: In children under 20 years, refractive development targets a cycloplegic refractive error of +0.5 to +1.5D, while presbyopes over 40 years generally have non-cycloplegic errors of ≥ +1D. Some papers suggest these periods are separated by a period of myopic refractive error (i.e., ≤ –0.50D), but this remains unclear. Hence, this work investigates the mean cycloplegic refractive error in adults aged between 20 – 40 years. Methods: In 2002 a cross-sectional study with stratified cluster sampling was performed on the population of Tehran, providing cycloplegic and non-cycloplegic refractive error data for the right eyes of 3,576 participants, aged 30.6 ± 18.6 years (range: 1–86 years). After grouping these data into age groups of 5 years, the refractive error histogram of each group was fitted to a Bigaussian function. The mean of the central, emmetropized peak was used to estimate the mean refractive error without the influence of myopia. Results: The mean cycloplegic refractive error at the emmetropized peak decreased from +1.10 ± 0.11D (95 % confidence interval) to +0.50 ± 0.04D before 20 years and remains stable at that value until the age of 50 years. The non-cycloplegic refractive error also sees a stable phase at 0.00 ± 0.04D between 15 – 45 years. After 45 – 50 years both cycloplegic and non-cycloplegic refractive error become more hypermetropic over time, +1.14 ± 0.12D at 75 years. Conclusions: The cycloplegic refractive error in adults is about +0.50D between 20 – 50 years, disproving the existence of the myopic period at those ages. © 2023 Spanish General Council of Optometry