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A Brief Overview of Common Radiopharmaceuticals for Detection of Infection/Inflammation in Nuclear Medicine Publisher



Vahidfar N1 ; Farzanefar S1 ; Bakhshi Kashi M1 ; Saboktakin F1 ; Sheikhzade P1 ; Eppard E2 ; Salehi Y1 ; Aghahosseini F1 ; Jahanbin M1 ; Sharifian F1 ; Abbasi M1
Authors
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Authors Affiliations
  1. 1. Department of Nuclear Medicine, IKH Complex, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, 1419733133, Iran
  2. 2. Department of Nuclear Medicine, University Hospital Magdeburg, Magdeburg, 39120, Germany

Source: Journal of Radioanalytical and Nuclear Chemistry Published:2024


Abstract

Inflammation comprises a heterogeneous category of disease with multiple clinical conditions and basically includes infection, acute inflammation, and chronic inflammation. One of the concerns for clinicians is the differentiation between tumor tissue and an inflammation site which significantly influences the treatment decisions. Recent progresses in nuclear medicine through the introducing of novel radiopharmaceuticals based on SPECT and PET, have been very promising in improvement of the specific differentiation between these two pathologies. In this review, the nuclear medicine approaches for the diagnosis of infection/inflammation, the differentiation between infection and inflammation, as well as the exclusion of tumor tissue, will be discussed. © Akademiai Kiado, Budapest, Hungary 2024.