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Introduction on Treatment for Infectious Diseases and Immunological Disorders Publisher



Sadeghalvad M1, 2, 3 ; Rezaei N1, 2, 3
Authors
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Authors Affiliations
  1. 1. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Encyclopedia of Infection and Immunity Published:2022


Abstract

Infectious diseases are still a significant cause of mortality and morbidity. Finding effective therapies has long been a major concern. While antibiotic discovery has greatly reduced infectious disease mortality and morbidity, the development of antimicrobial resistance threatens to reverse these benefits. However, the emergence of advanced technology has taken a significant step toward the development of novel treatments. Currently, treatments based on immunotherapy or immune system modulation by immunomodulatory agents are being used to treat a variety of viral and chronic illnesses. These therapies, including T cell therapies, cytokine therapy, monoclonal antibodies, and immune checkpoint blockade, have opened up a new path for the treatment of infectious diseases, immunological disorders (e.g., autoimmune diseases, immunodeficiencies), as well as malignancies that will be reviewed in this chapter. © 2022 Elsevier Inc. All rights reserved.
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