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Using Gold Nanoparticles in Diagnosis and Treatment of Melanoma Cancer Publisher Pubmed



Bagheri S1, 2, 3 ; Yasemi M4 ; Safaieqamsari E2, 3 ; Rashidiani J1 ; Abkar M5 ; Hassani M6 ; Mirhosseini SA7 ; Kooshki H1
Authors
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Authors Affiliations
  1. 1. Nano Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
  2. 2. Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Department of Immunology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Department of Cell and Molecular Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
  5. 5. Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  6. 6. Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Applied Microbiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Source: Artificial Cells# Nanomedicine and Biotechnology Published:2018


Abstract

Several studies have been devoted to clear functionalization of gold nanoparticles (AuNPs) in different fields such as cellular and molecular biology, microbiology, immunology and physiology. In line with the high diagnostic value of AuNPs, its therapeutic application has been intensively developed in tumour therapy, in recent years. One of the best clinical applications of AuNPs is its use in targeted delivery of anti-cancer drugs. Recent studies have focused on the application of AuNPs to treat melanoma–a malignant neoplasm sourced from melanocytes skin cells–with poor prognosis in advanced stages. Furthermore, early diagnosis can be successfully achieved through utilizing this technique even at early stages with localized distribution. Herein, this study details the previous researches focusing on the use of AuNPs as a novel diagnostic and therapeutic option in management of melanoma. © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group.
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