Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst

Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst Publisher

Mohamadkhani Y ; Peirow R ; Notash B ; Mahdavi M ; Rashidi Ranjbar P

Source: Journal of Organic Chemistry Published:2026

Abstract

A unique two-step, base-promoted rearrangement of post-Ugi products under copper catalysis is presented. Mechanistic studies revealed that the rearrangement proceeds via sequential amidation, with the copper(I) catalyst facilitating the reaction through carbonyl coordination. This work not only introduces a new synthetic route for the construction of conjugated imines but also provides valuable insights into the mechanistic pathways of post-Ugi rearrangements, paving the way for further exploration of intermolecular reactions and broader synthetic applications. © 2026 American Chemical Society

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Style	Citing Format
MLA	Mohamadkhani Y, et al.. "Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst." Journal of Organic Chemistry, vol. 91, no. 6, 2026, pp. 2327-2332.
APA	Mohamadkhani Y, Peirow R, Notash B, Mahdavi M, Rashidi Ranjbar P (2026). Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst. Journal of Organic Chemistry, 91(6), 2327-2332.
Chicago	Mohamadkhani Y, Peirow R, Notash B, Mahdavi M, Rashidi Ranjbar P. "Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst." Journal of Organic Chemistry 91, no. 6 (2026): 2327-2332.
Harvard	Mohamadkhani Y et al. (2026) 'Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst', Journal of Organic Chemistry, 91(6), pp. 2327-2332.
Vancouver	Mohamadkhani Y, Peirow R, Notash B, Mahdavi M, Rashidi Ranjbar P. Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst. Journal of Organic Chemistry. 2026;91(6):2327-2332.
BibTex	@article{ author = {Mohamadkhani Y and Peirow R and Notash B and Mahdavi M and Rashidi Ranjbar P}, title = {Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst}, journal = {Journal of Organic Chemistry}, volume = {91}, number = {6}, pages = {2327-2332}, year = {2026} }
RIS	TY - JOUR AU - Mohamadkhani Y AU - Peirow R AU - Notash B AU - Mahdavi M AU - Rashidi Ranjbar P TI - Serendipitous Two Successive Rearrangements of Ugi Adducts Promoted by a Base and a Copper Catalyst JO - Journal of Organic Chemistry VL - 91 IS - 6 SP - 2327 EP - 2332 PY - 2026 ER -

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