Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan

Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling Publisher

Ghasemi N¹ ; Yavari A¹ ; Bahadorikhalili S² ; Moazzam A¹ ; Hosseini S¹ ; Larijani B¹ ; Iraji A³ ; Moradi S³ ; Mahdavi M¹

Show Affiliations

1. Endocrinology and Metabolism Research Centre, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 1416634793, Iran
2. Department of Electronic Engineering, Universitat Rovira i Virgili, Tarragona, 43007, Spain
3. Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, 7134845794, Iran

Source: Inorganics Published:2022

Abstract

In this paper, magnetic chitosan is used as a support for the immobilization of copper catalyst (Cu@MChit). The fabricated catalyst is successfully synthesized and characterized by several techniques. The activity of Cu@MChit catalyst is evaluated in the synthesis of novel derivatives of 3-alkyl-2-arylthio-2,3-dihydroquinazolin-4(1H)-ones. The products are synthesized in three simple steps via Chan–Lam coupling reaction. The synthetic route is based on the reaction of isatoic anhydride and an amine, followed by the reaction with carbon disulfide. Cu@MChit-catalyzed reaction of the obtained intermediate with phenylboronic acid leads to the desired products. The scope of the reaction is confirmed by using various amine and phenylboronic acid derivatives and the products are obtained in high isolated yields. © 2022 by the authors.

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Mohammad Mahdavi (10)

Bagher Larijani (5)

Style	Citing Format
MLA	Ghasemi N, et al.. "Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling." Inorganics, vol. 10, no. 12, 2022, pp. -.
APA	Ghasemi N, Yavari A, Bahadorikhalili S, Moazzam A, Hosseini S, Larijani B, Iraji A, Moradi S, Mahdavi M (2022). Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling. Inorganics, 10(12), -.
Chicago	Ghasemi N, Yavari A, Bahadorikhalili S, Moazzam A, Hosseini S, Larijani B, Iraji A, Moradi S, Mahdavi M. "Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling." Inorganics 10, no. 12 (2022): -.
Harvard	Ghasemi N et al. (2022) 'Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling', Inorganics, 10(12), pp. -.
Vancouver	Ghasemi N, Yavari A, Bahadorikhalili S, Moazzam A, Hosseini S, Larijani B, et al.. Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling. Inorganics. 2022;10(12):-.
BibTex	@article{ author = {Ghasemi N and Yavari A and Bahadorikhalili S and Moazzam A and Hosseini S and Larijani B and Iraji A and Moradi S and Mahdavi M}, title = {Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling}, journal = {Inorganics}, volume = {10}, number = {12}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Ghasemi N AU - Yavari A AU - Bahadorikhalili S AU - Moazzam A AU - Hosseini S AU - Larijani B AU - Iraji A AU - Moradi S AU - Mahdavi M TI - Copper Catalyst-Supported Modified Magnetic Chitosan for the Synthesis of Novel 2-Arylthio-2,3-Dihydroquinazolin-4(1H)-One Derivatives Via Chan–Lam Coupling JO - Inorganics VL - 10 IS - 12 SP - EP - PY - 2022 ER -

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