Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19

Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19 Publisher Pubmed

Duivenvoorden R¹ ; Vart P² ; Noordzij M² ; Soares Dos Santos AC³ ; Zulkarnaev AB⁴ ; Franssen CFM² ; Kuypers D⁵ ; Demir E⁶ ; Rahimzadeh H⁷ ; Kerschbaum J⁸ ; Jager KJ⁹ ; Turkmen K¹⁰ ; Hemmelder MH^{11, 12} ; Schouten M¹³ Show All Authors

Duivenvoorden R¹
Vart P²
Noordzij M²
Soares Dos Santos AC³
Zulkarnaev AB⁴
Franssen CFM²
Kuypers D⁵
Demir E⁶
Rahimzadeh H⁷
Kerschbaum J⁸
Jager KJ⁹
Turkmen K¹⁰
Hemmelder MH^{11, 12}
Schouten M¹³
Rodriguezferrero ML¹⁴
Crespo M¹⁵
Gansevoort RT²
Hilbrands LB¹

Show Affiliations

1. Department of Nephrology, Radboud University Medical Center, Nijmegen, Netherlands
2. Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, 9713 GZ, Netherlands
3. Hospital das Clinicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
4. Surgical Department of Transplantation and Dialysis, Moscow Regional Research and Clinical Institute, Moscow, Russian Federation
5. Department of Nephrology, University Hospitals Leuven, Leuven, Belgium
6. Division of Nephrology, Department of Internal Medicine, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey
7. Department of Nephrology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
8. Austrian Dialysis and Transplant Registry, Department of Internal Medicine IV, Nephrology and Hypertension, Medical University Innsbruck, Innsbruck, Austria
9. ERA-EDTA Registry, Department of Medical Informatics, Amsterdam University Medical Center, Amsterdam Public Health Research Institute, Amsterdam, Netherlands
10. Division of Nephrology, Department of Internal Medicine, Necmettin Erbakan University, Meram School of Medicine, Konya, Turkey
11. Division of Nephrology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, Netherlands
12. CARIM School for Cardiovascular Disease, University of Maastricht, Maastricht, Netherlands
13. Department of Internal Medicine, Tergooi Hospital, Hilversum, Netherlands
14. Nephrology Department, Hospital General Universitario Gregorio Maranon, Madrid, Spain
15. Department of Nephrology, Hospital Del Mar Andand Hospital, Mar Medical Research Institute (IMIM), Barcelona, Spain

Source: Transplantation Published:2022

Abstract

Background. Kidney transplant patients are at high risk for coronavirus disease 2019 (COVID-19)-related mortality. However, limited data are available on longer-term clinical, functional, and mental health outcomes in patients who survive COVID-19. Methods. We analyzed data from adult kidney transplant patients in the European Renal Association COVID-19 Database who presented with COVID-19 between February 1, 2020, and January 31, 2021. Results. We included 912 patients with a mean age of 56.7 (±13.7) y. 26.4% were not hospitalized, 57.5% were hospitalized without need for intensive care unit (ICU) admission, and 16.1% were hospitalized and admitted to the ICU. At 3 mo follow-up survival was 82.3% overall, and 98.8%, 84.2%, and 49.0%, respectively, in each group. At 3 mo follow-up biopsy-proven acute rejection, need for renal replacement therapy, and graft failure occurred in the overall group in 0.8%, 2.6%, and 1.8% respectively, and in 2.1%, 10.6%, and 10.6% of ICU-admitted patients, respectively. Of the surviving patients, 83.3% and 94.4% reached their pre-COVID-19 physician-reported functional and mental health status, respectively, within 3 mo. Of patients who had not yet reached their prior functional and mental health status, their treating physicians expected that 79.6% and 80.0%, respectively, still would do so within the coming year. ICU admission was independently associated with a low likelihood to reach prior functional and mental health status. Conclusions. In kidney transplant recipients alive at 3-mo follow-up, clinical, physician-reported functional, and mental health recovery was good for both nonhospitalized and hospitalized patients. Recovery was, however, less favorable for patients who had been admitted to the ICU. © 2022 Lippincott Williams and Wilkins. All rights reserved.

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Style	Citing Format
MLA	Duivenvoorden R, et al.. "Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19." Transplantation, vol. 106, no. 5, 2022, pp. 1012-1023.
APA	Duivenvoorden R, Vart P, Noordzij M, Soares Dos Santos AC, Zulkarnaev AB, Franssen CFM, Kuypers D, Demir E, Rahimzadeh H, Kerschbaum J, Jager KJ, Turkmen K, Hemmelder MH, Schouten M, Rodriguezferrero ML, Crespo M, Gansevoort RT, Hilbrands LB (2022). Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19. Transplantation, 106(5), 1012-1023.
Chicago	Duivenvoorden R, Vart P, Noordzij M, Soares Dos Santos AC, Zulkarnaev AB, Franssen CFM, Kuypers D, et al.. "Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19." Transplantation 106, no. 5 (2022): 1012-1023.
Harvard	Duivenvoorden R et al. (2022) 'Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19', Transplantation, 106(5), pp. 1012-1023.
Vancouver	Duivenvoorden R, Vart P, Noordzij M, Soares Dos Santos AC, Zulkarnaev AB, Franssen CFM, et al.. Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19. Transplantation. 2022;106(5):1012-1023.
BibTex	@article{ author = {Duivenvoorden R and Vart P and Noordzij M and Soares Dos Santos AC and Zulkarnaev AB and Franssen CFM and Kuypers D and Demir E and Rahimzadeh H and Kerschbaum J and Jager KJ and Turkmen K and Hemmelder MH and Schouten M and Rodriguezferrero ML and Crespo M and Gansevoort RT and Hilbrands LB}, title = {Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19}, journal = {Transplantation}, volume = {106}, number = {5}, pages = {1012-1023}, year = {2022} }
RIS	TY - JOUR AU - Duivenvoorden R AU - Vart P AU - Noordzij M AU - Soares Dos Santos AC AU - Zulkarnaev AB AU - Franssen CFM AU - Kuypers D AU - Demir E AU - Rahimzadeh H AU - Kerschbaum J AU - Jager KJ AU - Turkmen K AU - Hemmelder MH AU - Schouten M AU - Rodriguezferrero ML AU - Crespo M AU - Gansevoort RT AU - Hilbrands LB TI - Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of Covid-19 JO - Transplantation VL - 106 IS - 5 SP - 1012 EP - 1023 PY - 2022 ER -

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