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A Highly Efficient Method for the Synthesis of Novel 1'H-Spiro[Indene-2,2'-Quinazoline]-1,3,4'(3'H)-Trione Derivatives Publisher



Sadatebrahimi SE1 ; Irannezhad S1 ; Moghimi S2 ; Yahyameymandi A1 ; Mahdavi M2 ; Shafiee A2 ; Foroumadi A2
Authors
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Authors Affiliations
  1. 1. International Campus, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Medicinal Chemistry, Faculty of Pharmacy, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Chemical Research Published:2015


Abstract

A series of novel ninhydrin-derived spiro-quinazolinone derivatives in moderate to good yields have been synthesised through a ferric chloride catalysed reaction in 1,2-dichloroethane.