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An Efficient Approach to the Synthesis of Coumarin-Fused Dihydropyridinones Publisher



Firoozpour L1 ; Nikookar H2 ; Moghimi S1 ; Mahdavi M3 ; Asadipour A4 ; Ranjbar PR2 ; Foroumadi A4, 5
Authors
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Authors Affiliations
  1. 1. Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. School of Chemistry, College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran
  3. 3. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Medicinal Chemistry, Faculty of Pharmacy and Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, I-Kerman, Iran
  5. 5. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Heterocyclic Communications Published:2017


Abstract

3,4-Dihydro-2H-chromeno[4,3-b]pyridine-2,5(1H)-dione derivatives were efficiently prepared by the reaction of 4-hydroxycoumarin, ammonia, aromatic aldehyde and Meldrum's acid in refluxing 1-propanol. © 2017 Walter de Gruyter GmbH, Berlin/Boston.