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Using Chatgpt to Predict the Future of Personalized Medicine Publisher Pubmed



Patrinos GP1, 2, 3 ; Sarhangi N4 ; Sarrami B5 ; Khodayari N6 ; Larijani B7 ; Hasanzad M4, 8
Authors
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Authors Affiliations
  1. 1. Department of Pharmacy, School of Health Sciences, University of Patras, Patras, 26504, Greece
  2. 2. Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, P.O. Box 15551, Abu Dhabi, United Arab Emirates
  3. 3. United Arab Emirates University, Zayed Center for Health Sciences, Al Ain, P.O. Box 15551, Abu Dhabi, United Arab Emirates
  4. 4. Personalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 1411713119, Iran
  5. 5. Missouri Pharmacogenomics Consulting, St. Mo, St. Louis, 63011, MO, United States
  6. 6. Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, 32610-0225, FL, United States
  7. 7. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 1411713119, Iran
  8. 8. Medical Genomics Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, 193951459, Iran

Source: Pharmacogenomics Journal Published:2023


Abstract

Personalized medicine is a novel frontier in health care that is based on each person’s unique genetic makeup. It represents an exciting opportunity to improve the future of individualized health care for all individuals. Pharmacogenomics, as the main part of personalized medicine, aims to optimize and create a more targeted treatment approach based on genetic variations in drug response. It is predicted that future treatments will be algorithm-based instead of evidence-based that will consider a patient’s genetic, transcriptomic, proteomic, epigenetic, and lifestyle factors resulting in individualized medication. A generative pretrained transformer (GPT) is an artificial intelligence (AI) tool that generates language resembling human-like writing enabling users to engage in a manner that is practically identical to speaking with a human being. GPT’s predictive algorithms can respond to questions that have never been addressed. Chat Generative Pretrained Transformer (ChatGPT) is an AI chatbot’s advanced with conversational capabilities. In the present study, questions were asked from ChatGPT about the future of personalized medicine and pharmacogenomics. ChatGPT predicted both to be a promising approach with a bright future that holds great promises in improving patient outcomes and transforming the field of medicine. But it still has several limitations that need to be solved. © 2023, The Author(s), under exclusive licence to Springer Nature Limited.