Tehran University of Medical Sciences

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Principles of Precision Medicine Publisher



Larijani B1 ; Sarhangi N1 ; Hasanzad M1, 3 ; Meybodi HRA2
Authors
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Authors Affiliations
  1. 1. Personalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Medical Genomics Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

Source: Precision Medicine in Clinical Practice Published:2022


Abstract

Precision medicine principles have long been a pillar of medical practice. Precision (personalized) medicine is a new medical approach that uses a patient’s genetic profile to guide decisions about disease prevention, diagnosis, and treatment. The goal of precision medicine is to combine current medicine with molecular breakthroughs to target patients individually and increase the efficacy and effectiveness of the therapeutic strategy. Pharmacogenomics (PGx) is one of the most important components of personalized medicine now used to describe how various genetic variants throughout the genome can affect drug response, whereas pharmacogenetics is the study of single DNA variation related to the drug response. The concept of precision medicine appears to hold promising results, and some of the potential benefits of precision medicine are increasing the effectiveness of care, preventive medicine, cost-effectiveness, new disease taxonomy, and population healthcare. In this chapter, we present a review of principles of precision medicine. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022.
1. Genomic Medicine on the Frontier of Precision Medicine, Journal of Diabetes and Metabolic Disorders (2022)
2. Principles of Pharmacogenomics and Pharmacogenetics, Precision Medicine in Clinical Practice (2022)
3. Precision Medicine Journey Through Omics Approach, Journal of Diabetes and Metabolic Disorders (2022)
4. Personalized Cancer Vaccine, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2019)
5. Personalized Cancer Vaccine, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
6. Precision Medicine in Endocrinology Practice, Precision Medicine in Clinical Practice (2022)
7. A Systematic Review of Mirnas As Biomarkers in Osteoporosis Disease, Journal of Diabetes and Metabolic Disorders (2021)
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