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Burden of Musculoskeletal Disorders in Iran During 1990–2017: Estimates From the Global Burden of Disease Study 2017 Publisher Pubmed



Shahrezaee M1 ; Keshtkari S2 ; Moradilakeh M3 ; Abbasifard M4, 5 ; Alipour V6, 7 ; Amini S8 ; Arabloo J6 ; Arzani A9 ; Bakhshaei M10 ; Barzegar A11 ; Bijani A12 ; Dianatinasab M13, 14 ; Eskandarieh S15 ; Gheshlagh RG16 Show All Authors
Authors
  1. Shahrezaee M1
  2. Keshtkari S2
  3. Moradilakeh M3
  4. Abbasifard M4, 5
  5. Alipour V6, 7
  6. Amini S8
  7. Arabloo J6
  8. Arzani A9
  9. Bakhshaei M10
  10. Barzegar A11
  11. Bijani A12
  12. Dianatinasab M13, 14
  13. Eskandarieh S15
  14. Gheshlagh RG16
  15. Ghashghaee A6, 17
  16. Heidarisoureshjani R18
  17. Irvani SSN19
  18. Lahimchi A20
  19. Maleki S21
  20. Manafi N22, 23
  21. Manafi A24
  22. Mansournia MA25
  23. Mohammadianhafshejani A26
  24. Bandpei MAM27
  25. Moradzadeh R28
  26. Naderi M21
  27. Pakshir K29
  28. Rafiei A30, 31
  29. Rashedi V32
  30. Rezaei N33, 34
  31. Rezapour A6
  32. Sahraian MA15
  33. Shahabi S35
  34. Shamsi M36
  35. Soheili A37
  36. Soroush A36
  37. Zamani M38
  38. Mohajer B1
  39. Farzadfar F39
Show Affiliations
Authors Affiliations
  1. 1. Department of Orthopedic Surgery, AJA University of Medical Sciences, Tehran, Iran
  2. 2. Department of Internal Medicine, AJA University of Medical Sciences, Tehran, Iran
  3. 3. Preventive Medicine and Public Health Research Center, Iran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Internal Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  5. 5. Clinical Research Development Unit, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  6. 6. Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Health Economics, Iran University of Medical Sciences, Tehran, Iran
  8. 8. Department of Health Services Management, Arak University of Medical Sciences, Arak, Iran
  9. 9. Center for Non-Communicable Pediatric Diseases, Health Research Institute, School of Nursing and Midwifery, Babol University of Medical Sciences, Babol, Iran
  10. 10. Department of Anesthesiology, Hamedan University of Medical Sciences, Hamadan, Iran
  11. 11. Department of Occupational Health Engineering, Kermanshah University of Medical Sciences, Kermanshah, Iran
  12. 12. Social Determinants of Health Research Center, Babol University of Medical Sciences, Babol, Iran
  13. 13. Department of Epidemiology, Shahroud University of Medical Sciences, Shahroud, Iran
  14. 14. Department of Epidemiology, Shiraz University of Medical Sciences, Shiraz, Iran
  15. 15. Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
  16. 16. Faculty of Nursing and Midwifery, Kurdistan University of Medical Sciences, Sanandaj, Iran
  17. 17. Student Research Committee, Iran University of Medical Sciences, Tehran, Iran
  18. 18. School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  19. 19. Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  20. 20. First Faculty of Medicine, Charles University, Prague, Czech Republic
  21. 21. Clinical Research Development Center, Taleghani and Imam Ali Hospitals, Kermanshah University of Medical Sciences, Kermanshah, Iran
  22. 22. Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada
  23. 23. Department of Ophthalmology, Iran University of Medical Sciences, Tehran, Iran
  24. 24. Department of Plastic Surgery, Iran University of Medical Sciences, Tehran, Iran
  25. 25. Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran
  26. 26. Department of Epidemiology and Biostatistics, Shahrekord University of Medical Sciences, Shahrekord, Iran
  27. 27. Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
  28. 28. Department of Epidemiology, Arak University of Medical Sciences, Arak, Iran
  29. 29. Department of Parasitology and Mycology, Shiraz University of Medical Sciences, Shiraz, Iran
  30. 30. Department of Immunology, Mazandaran University of Medical Sciences, Sari, Iran
  31. 31. Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran
  32. 32. School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, Iran
  33. 33. Research Center for Immunodeficiencies, Tehran University of Medical Sciences, Tehran, Iran
  34. 34. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  35. 35. Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  36. 36. School of Rehabilitation Sciences, Kermanshah University of Medical Sciences, Kermanshah, Iran
  37. 37. Nursing Care Research Center, Semnan University of Medical Sciences, Semnan, Iran
  38. 38. Student Research Committee, Babol University of Medical Sciences, Babol, Iran
  39. 39. Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Archives of Osteoporosis Published:2020


Abstract

Summary: Musculoskeletal diseases (MSDs) are the leading cause of disability and facing them demands updated reports on their burden for efficient policymaking. We showed Iran had the highest female-to-male ratio and highest increase in the burden of musculoskeletal diseases, in the past three decades, worldwide. We further confirmed the role of population aging as the main cause. Purpose: MSDs comprise most of the top causes of years lived with disability (YLDs) worldwide and are rapidly increasing in lower- and middle-income countries. Here, we present disability and mortality due to MSDs in Iran at the national level from 1990 to 2017. Methods: We used Global Burden of Disease (GBD) 2017 Study data and standard methodology and presented the burden of MSDs in rates of years of life lost (YLLs), YLDs, and disability-adjusted life years (DALYs) during 1990–2017, for population aged ≥ 5 years old. We further explored attributable risk factors and decomposed the changing trend in DALYs to assess underlying causes. Results: In Iran, MSDs were responsible for 1.82 million (95%uncertainty interval [UI] 1.3–2.4) DALYs, in 2017. During the past 28 years, with 1.75% annualized percentage change (APC), Iran had the highest percentage increase in the all-ages MSD DALYs rate worldwide, while the age-standardized DALYs APC was negligible. Low back pain was the greatest contributor to DALYs and caused 4.5% of total DALYs. The female population is experiencing considerably higher burden of MSDs, with 115% and 48% higher all-ages YLLs and YLDs rates per 100,000, respectively (YLLs 28.7; YLDs 2629.1), than males (YLLs 13.2; YLDs 1766.1). However, due to wide UIs, difference was not significant. Only 17.6% of MSD YLDs are attributable to assessed risk factors. Conclusion: Despite that MSDs are rising as an important cause of disability in Iran, these conditions are not sufficiently addressed in health policies. There is urgent need for cross-sectoral engagement, especially addressing the MSDs in females. © 2020, International Osteoporosis Foundation and National Osteoporosis Foundation.
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