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Estimating Mortality and Disability in Peru Before the Covid-19 Pandemic: A Systematic Analysis From the Global Burden of the Disease Study 2019 Publisher Pubmed



Riosblancas MJ1, 2 ; Pandorobles V3 ; Razo C4 ; Carcamo CP5 ; Mendoza W6 ; Pachecobarrios K7, 8 ; Miranda JJ9, 10 ; Lansingh VC11, 12 ; Demie TG13 ; Saha M14, 15 ; Okonji OC16 ; Yigit A17 ; Cahuanahurtado L5 ; Chaconuscamaita PR18 Show All Authors
Authors
  1. Riosblancas MJ1, 2
  2. Pandorobles V3
  3. Razo C4
  4. Carcamo CP5
  5. Mendoza W6
  6. Pachecobarrios K7, 8
  7. Miranda JJ9, 10
  8. Lansingh VC11, 12
  9. Demie TG13
  10. Saha M14, 15
  11. Okonji OC16
  12. Yigit A17
  13. Cahuanahurtado L5
  14. Chaconuscamaita PR18
  15. Bernabe E19
  16. Culquichicon C20
  17. Chirinoscaceres JL5
  18. Cardenas R21
  19. Alcalderabanal JE22
  20. Barrera FJ23
  21. Quintanilla BPA24, 25
  22. Shorofi SA26, 27
  23. Wickramasinghe ND28
  24. Ferreira N29
  25. Almidani L30, 31
  26. Gupta VK32
  27. Karimi H33
  28. Alayu DS34
  29. Benziger CP35
  30. Fukumoto T36
  31. Mostafavi E37, 38
  32. Redwan EMM39, 40
  33. Gebrehiwot M41
  34. Khatab K42
  35. Koyanagi A43, 44
  36. Krapp F45, 46
  37. Lee S47
  38. Noori M48
  39. Qattea I49
  40. Rosenthal VD50
  41. Sakshaug JW51, 52
  42. Wagaye B52, 53
  43. Zare I54
  44. Ortegaaltamirano DV55
  45. Murillozamora E56, 57
  46. Vervoort D58
  47. Silva DAS59
  48. Oulhaj A60
  49. Herreraserna BY61
  50. Mehra R62
  51. Amirbehghadami M63, 64
  52. Adib N65
  53. Cortes S66, 67
  54. Dang AK68
  55. Nguyen BT69
  56. Mokdad AH69
  57. Hay SI69
  58. Murray CJL69
  59. Lozano R69
  60. Garcia PJ5
Show Affiliations
Authors Affiliations
  1. 1. School of Public Health of Mexico, National Institute of Public Health, Cuernavaca, Mexico
  2. 2. Carlos Slim Foundation, Mexico City, Mexico
  3. 3. Infectious Disease Research Center, National Institute of Public Health, Cuernavaca, Mexico
  4. 4. Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States
  5. 5. School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru
  6. 6. Peru Country Office, United Nations Population Fund (UNFPA), Lima, Peru
  7. 7. Spaulding Rehabilitation Hospital, Harvard University, Boston, MA, United States
  8. 8. Universidad San Ignacio de Loyola (University of Saint Ignatius of Loyola), Lima, Peru
  9. 9. CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia (Cayetano Heredia Peruvian University), Lima, Peru
  10. 10. Department of Medicine, Universidad Peruana Cayetano Heredia (Cayetano Heredia Peruvian University), Lima, Peru
  11. 11. HelpMeSee, New York, NY, United States
  12. 12. Mexican Institute of Ophthalmology, Queretaro, Mexico
  13. 13. School of Public Health, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia
  14. 14. Department of Humanities and Social Sciences, Deakin University, Melbourne, VIC, Australia
  15. 15. Department of Human-Centred Computing, Monash University, Melbourne, VIC, Australia
  16. 16. School of Pharmacy, University of the Western Cape, Cape Town, South Africa
  17. 17. Department of Health Management, Suleyman Demirel Universitesi (Suleyman Demirel University), Isparta, Turkey
  18. 18. Emerge, Emerging Diseases and Climate Change Research Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru
  19. 19. Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, United Kingdom
  20. 20. Universidad Privada Norbert Wiener, Centro de Investigacion Epidemiologica en Salud Global, Lima, Peru
  21. 21. Department of Health Care, Metropolitan Autonomous University, Mexico City, Mexico
  22. 22. Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico
  23. 23. Department of Epidemiology, Harvard University, Boston, MA, United States
  24. 24. The Judith Lumley Centre, La Trobe University, Melbourne, VIC, Australia
  25. 25. San Martin de Porres University, Lima, Peru
  26. 26. Medical-Surgical Nursing, Mazandaran University of Medical Sciences, Sari, Iran
  27. 27. College of Nursing and Health Sciences, Flinders University, Adelaide, SA, Australia
  28. 28. Department of Community Medicine, Rajarata University of Sri Lanka, Anuradhapura, Sri Lanka
  29. 29. Department of Social Sciences, University of Nicosia, Nicosia, Cyprus
  30. 30. Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom
  31. 31. Doheny Image Reading and Research Lab (DIRRL) - Doheny Eye Institute, University of California, Los Angeles, Los Angeles, CA, United States
  32. 32. Faculty of Medicine Health and Human Sciences, Macquarie University, Sydney, NSW, Australia
  33. 33. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  34. 34. Department of Epidemiology and Biostatistics, University of Gondar, Gondar, Ethiopia
  35. 35. Heart and Vascular Center, Essentia Health, Duluth, MN, United States
  36. 36. Department of Dermatology, Kobe University, Kobe, Japan
  37. 37. Department of Medicine, Stanford University, Palo Alto, CA, United States
  38. 38. Stanford Cardiovascular Institute, Stanford University, Palo Alto, CA, United States
  39. 39. Department Biological Sciences, King Abdulaziz University, Jeddah, Egypt
  40. 40. Department of Protein Research, Research and Academic Institution, Alexandria, Egypt
  41. 41. Department of Environmental Health, Wollo University, Dessie, Ethiopia
  42. 42. Health and Wellbeing, Sheffield Hallam University, Sheffield, United Kingdom
  43. 43. Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Sant Boi de Llobregat, Spain
  44. 44. Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain
  45. 45. Instituto de Medicina Tropical Alexander von Humboldt (Alexander von Humboldt Institute for Tropical Medicine), Cayetano Heredia University, Lima, Peru
  46. 46. Doctoral School of Biomedical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
  47. 47. Department of Precision Medicine, Sungkyunkwan University, Suwon-si, South Korea
  48. 48. Student Research Committee, Iran University of Medical Sciences, Tehran, Iran
  49. 49. Department of Neonatology, Case Western Reserve University, Cleveland, OH, United States
  50. 50. International Nosocomial Infection Control Consortium, Independent Consultant, Buenos Aires, Argentina
  51. 51. Institute for Employment Research, University of Warwick, Coventry, United Kingdom
  52. 52. Department of Statistics, Ludwig Maximilians University, Munich, Germany
  53. 53. Infection Prevention and Control and Water, Sanitation and Hygiene Unit, Ethiopian Public Health Institute, Addis Ababa, Ethiopia
  54. 54. Research and Development Department, Sina Medical Biochemistry Technologies Co. Ltd., Shiraz, Iran
  55. 55. Health Systems Research Center, National Institute of Public Health, Cuernavaca, Mexico
  56. 56. Clinical Epidemiology Research Unit, Mexican Institute of Social Security, Villa de Alvarez, Mexico
  57. 57. Postgraduate in Medical Sciences, Universidad de Colima, Colima, Mexico
  58. 58. Department of Health Policy and Management, Johns Hopkins University, Baltimore, MD, United States
  59. 59. Department of Physical Education, Federal University of Santa Catarina, Florianopolis, Brazil
  60. 60. Department of Epidemiology and Population Health, Khalifa University, Abu Dhabi, United Arab Emirates
  61. 61. Departamento de Salud Oral (Department of Oral Health), Universidad Autonoma de Manizales (Autonomous University of Manizales), Manizales, Colombia
  62. 62. Food Science and Technology, Maharishi Markandeshwar (Deemed to be University), Haryana, Ambala, India
  63. 63. Road Traffic Injury Research Center, Iranian International Safe Community Support Center, Tabriz University of Medical Sciences, Tabriz, Iran
  64. 64. Department of Health Service Management, Iranian Center of Excellence in Health Management, Tabriz, Iran
  65. 65. Department of Veterinary Pathobiology, Shahid Bahonar University of Kerman, Kerman, Iran
  66. 66. Department of Public Health, Pontifical Catholic University of Chile, Santiago, Chile
  67. 67. Research Line in Environmental Exposures and Health Effects at Population Level, Centro de Desarrollo Urbano Sustentable (CEDEUS), Advanced Center for Chronic Diseases (ACCDIS), Santiago, Chile
  68. 68. Institute for Global Health Innovations, Duy Tan University, Da Nang, Viet Nam
  69. 69. Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, United States

Source: Frontiers in Public Health Published:2023


Abstract

Background: Estimating and analyzing trends and patterns of health loss are essential to promote efficient resource allocation and improve Peru’s healthcare system performance. Methods: Using estimates from the Global Burden of Disease (GBD), Injuries, and Risk Factors Study (2019), we assessed mortality and disability in Peru from 1990 to 2019. We report demographic and epidemiologic trends in terms of population, life expectancy at birth (LE), mortality, incidence, prevalence, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) caused by the major diseases and risk factors in Peru. Finally, we compared Peru with 16 countries in the Latin American (LA) region. Results: The Peruvian population reached 33.9 million inhabitants (49.9% women) in 2019. From 1990 to 2019, LE at birth increased from 69.2 (95% uncertainty interval 67.8–70.3) to 80.3 (77.2–83.2) years. This increase was driven by the decline in under-5 mortality (−80.7%) and mortality from infectious diseases in older age groups (+60 years old). The number of DALYs in 1990 was 9.2 million (8.5–10.1) and reached 7.5 million (6.1–9.0) in 2019. The proportion of DALYs due to non-communicable diseases (NCDs) increased from 38.2% in 1990 to 67.9% in 2019. The all-ages and age-standardized DALYs rates and YLLs rates decreased, but YLDs rates remained constant. In 2019, the leading causes of DALYs were neonatal disorders, lower respiratory infections (LRIs), ischemic heart disease, road injuries, and low back pain. The leading risk factors associated with DALYs in 2019 were undernutrition, high body mass index, high fasting plasma glucose, and air pollution. Before the COVID-19 pandemic, Peru experienced one of the highest LRIs-DALYs rates in the LA region. Conclusion: In the last three decades, Peru experienced significant improvements in LE and child survival and an increase in the burden of NCDs and associated disability. The Peruvian healthcare system must be redesigned to respond to this epidemiological transition. The new design should aim to reduce premature deaths and maintain healthy longevity, focusing on effective coverage and treatment of NCDs and reducing and managing the related disability. Copyright © 2023 Rios-Blancas, Pando-Robles, Razo, Carcamo, Mendoza, Pacheco-Barrios, Miranda, Lansingh, Demie, Saha, Okonji, Yigit, Cahuana-Hurtado, Chacon-Uscamaita, Bernabe, Culquichicon, Chirinos-Caceres, Cardenas, Alcalde-Rabanal, Barrera, Quintanilla, Shorofi, Wickramasinghe, Ferreira, Almidani, Gupta, Karimi, Alayu, Benziger, Fukumoto, Mostafavi, Redwan, Gebrehiwot, Khatab, Koyanagi, Krapp, Lee, Noori, Qattea, Rosenthal, Sakshaug, Wagaye, Zare, Ortega-Altamirano, Murillo-Zamora, Vervoort, Silva, Oulhaj, Herrera-Serna, Mehra, Amir-Behghadami, Adib, Cortes, Dang, Nguyen, Mokdad, Hay, Murray, Lozano and Garcia.
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