Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Subtype Distribution of Blastocystis Sp. Isolated From Humans in Iran: A Systematic Review and Meta-Analysis Publisher



Maleki B1 ; Olfatifar M2 ; Dodangeh S3 ; Ahmadi N4 ; Gorgipour M1 ; Javanmard E5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  2. 2. Gastroenterology and Hepatology Diseases Research Center, Qom University of Medical Sciences, Qom, Iran
  3. 3. Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
  4. 4. Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Gastroenterology and Hepatology from Bed to Bench Published:2022


Abstract

Aim: This systematic review and meta-Analysis evaluated the subtyped Blastocystis sp. isolated from humans in Iran. Background: Blastocystis sp. is an anaerobic intestinal protozoan that infects humans as well as domestic and wild animals, i.e. mammals, amphibians, reptiles, and arthropods. Methods: A comprehensive search for papers published before April 2022 was undertaken utilizing English and Persian databases. The following MeSH keywords were used in the electronic search: (Blastocystis sp.) AND (molecular OR subtype) AND (prevalence OR epidemiology) AND Iran. The quality of the included studies was evaluated. Thereafter, a random-effects meta-Analysis was conducted to estimate the pooled prevalence and odds ratios regarding the included studies. Results: A total of 32 studies comprised of five case-control studies and 27 cross-sectional studies met the eligibility criteria. The overall pooled prevalence of subtyped Blastocystis sp. in Iran was estimated to be 10% (95% confidence interval: 6 to 15%). Eight subtypes of Blastocystis sp. (ST1-ST7 and ST9) were identified in our study, of which ST3 was the most common subtype (0.04); 0.02-0.07). The difference in subtypes between two case and control groups in reported studies was not significant, but the odds ratio of infection by ST3 (0.98; 95% CI, 0.30 to 3.20) was higher in cases. Conclusion: The current systematic review showed that with the exception of ST8 and ST12, all human Blastocystis sp. Subtypes reported in the world are found in different parts of Iran. © 2022 Research Institute for Gastroenterology and Liver Diseases. All rights reserved.
Related Docs
View other Related Docs
1. Inter- and Intra-Subtype Variation of Blastocystis Subtypes Isolated From Diarrheic and Non-Diarrheic Patients in Iran, Infection# Genetics and Evolution (2017)
2. Prevalence and Molecular Subtyping of Blastocystis From Patients With Irritable Bowel Syndrome, Inflammatory Bowel Disease and Chronic Urticaria in Iran, Acta Parasitologica (2020)
3. Subtypes Distribution and Frequency of Blastocystis Sp. Isolated From Diarrheic and Non-Diarrheic Patients, Iranian Journal of Parasitology (2017)
4. Association Between Blastocystis Sp. Infection and Immunocompromised Patients: A Systematic Review and Meta-Analysis, Environmental Science and Pollution Research (2021)
5. Prevalence of Intestinal Parasitic Infections in Patients With Diabetes: A Systematic Review and Meta-Analysis, International Health (2024)
6. Are Intestinal Helminths Playing a Positive Role in Tuberculosis Risk? a Systematic Review and Meta-Analysis, PLoS ONE (2019)
7. Infection and Immunity, Clinical Immunology (2022)
8. Helicobacter Pylori Infection and Risk of Preeclampsia: A Systematic Review and Meta-Analysis, Journal of Maternal-Fetal and Neonatal Medicine (2019)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (1)
Mahdi Mohebali (1)
Other Related Docs
9. Toxocara Spp. Infection and Risk of Childhood Asthma: A Systematic Review and Meta-Analysis, Acta Tropica (2018)