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Infection and Immunity Publisher



Saleki K1, 2 ; Razi S3, 4, 5 ; Rezaei N5, 6, 7
Authors
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Authors Affiliations
  1. 1. Student Research Committee, Babol University of Medical Sciences, Babol, Iran
  2. 2. USERN Office, Babol University of Medical Sciences, Babol, Iran
  3. 3. Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  4. 4. School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Clinical Immunology Published:2022


Abstract

Human infections are caused by bacteria, fungi, parasites, and viruses. While the human body defends against infections consistently via innate and adaptive immune responses, the face of infection in human disease is changing globally. For instance, the immunocompromised population is on the rise, mainly due to extensive chemotherapies, immunosuppressive treatment for transplantation, and emerging infections such as infection with Human immunodeficiency virus (HIV). In this light, the development of effective immunological diagnostic tests and immune-mediating treatments may be vital. The present chapter provides an updated review on definition and epidemiology, molecular mechanisms, diagnosis, and treatment of infectious diseases, as well as highlights areas of further research in the field. © 2023 Elsevier Inc. All rights reserved.
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