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A Practical Approach for the Synthesis of Novel Triazolo-Fused Benzazepine Derivatives Using a Multi-Component Reaction and an Intramolecular C-H Arylation Publisher



Homami SS1 ; Rezaei Z2
Authors

Source: Journal of Chemical Research Published:2016


Abstract

An efficient and straightforward method has been developed for the preparation of triazolo-fused benzazepines by a facile, one-pot Ugi multi-component reaction/click reaction. In this strategy, the Ugi-reaction products were coupled by a click reaction, thus integrating the triazole fragment into the benzazepine structure using an intramolecular C-H arylation. The corresponding products were obtained in good yields without unfavourable by-products.
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