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Managing Patients With Side Effects and Adverse Events to Immunoglobulin Therapy Publisher Pubmed



Azizi G1, 2 ; Abolhassani H2, 3 ; Asgardoon MH2 ; Shaghaghi S2, 4 ; Negahdari B5 ; Mohammadi J6 ; Rezaei N2 ; Aghamohammadi A2
Authors
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Authors Affiliations
  1. 1. Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran
  2. 2. Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Childrens Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden
  4. 4. Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  5. 5. School of Advanced Technologies in Medicine, Department of Medical Biotechnology, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Biomedical Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran

Source: Expert Review of Clinical Pharmacology Published:2016


Abstract

Immunoglobulin therapy has not only served as a lifesaving approach for the prevention and treatment of infections in primary and secondary immunodeficiency diseases, but has also been used as an immunomodulatory agent for autoimmune and inflammatory disorders and to provide passive immunity for some infectious diseases. Most of the adverse effects associated with immunoglobulin therapy are mild, transient and self-limiting. However, serious side effects also occur. Therefore, to minimize the adverse events of immunoglobulin therapy, specialist review of patient clinical status and immunoglobulin products, in addition to selection of appropriate treatment strategy for the management of patients with associated side effects and adverse events, are crucial. © 2015 Taylor & Francis.