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Histological Changes in the Periosteum Following Subperiosteal Expansion in Rabbit Scalp Publisher Pubmed



Kiani MT1 ; Takzare N2 ; Khoshzaban A3 ; Jalilianfar E4 ; Aghajanpour L5 ; Tabrizi R6
Authors
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Authors Affiliations
  1. 1. Assistant Professor of Oral and Maxillofacial Surgery, Shahid Beheshti Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Anatomy Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Senior Researcher, Iranian Tissue Bank and Research Center, Imam Khomeini Medical Complex Hospital, Bio-Dental Materials Department, Dental Faculty, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Dentist, Tehran University of Medical Sciences, International Campus, Tehran, Iran
  5. 5. Researcher, Stem Cell Preparation Unit, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Associate Professor of Oral and Maxillofacial Surgery, Shahid Beheshti Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Journal of Oral and Maxillofacial Surgery Published:2018


Abstract

Purpose: In intraoral bone grafting, tension-free coverage of the recipient site with periosteal flap results in optimal wound closure. Tissue expansion could be a suitable modality to obtain soft tissue in the oral cavity. The aim of this study was to assess the histology of the periosteum after subperiosteal expansion in the rabbit scalp. Materials and Methods: In this animal study, 6 rectangular tissue expanders were placed in the skulls of 6 male white New Zealand rabbits; in 6 control rabbits, an incision was made to the periosteum but no expansion was performed. Three months after the surgeries, the rabbits were sacrificed and tissue samples were stained with hematoxylin and eosin and Masson trichrome. Results: The number of osteoblasts, fibroblasts, and blood vessels and the density of collagen fibers were significantly increased in the experimental group compared with the control group (P <.001). Conclusions: Subperiosteal tissue expansion in the rabbit scalp markedly increased the histologic components of the periosteum involved in bone regeneration. © 2017 American Association of Oral and Maxillofacial Surgeons
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