Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Myoring Implantation With and Without Corneal Collagen Crosslinking for the Management of Keratoconus Publisher



Mohammadpour M1 ; Masoumi A1 ; Dehghan M1 ; Hashemian MN1 ; Karami SA1 ; Mahmoudi A1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Ophthalmic and Vision Research Published:2020


Abstract

Purpose: To evaluate the safety and efficacy of femtosecond laser-assisted MyoRing implantation with concurrent corneal collagen crosslinking (CXL) compared to MyoRing alone for the treatment of progressive keratoconus. Methods: A total of 60 patients were enrolled in this randomized controlled trial. The patients were randomly allocated into two groups. In the first group, MyoRing was implanted, while in the second, it was inserted in the corneal stroma using the same technique, along with simultaneous CXL. Visual, refractive, topographic, and abberometric outcomes were measured preoperatively and at every postoperative visit. Results: Data of 47 patients were available at the end of the study; 28 in the MyoRing group and 19 in the MyoRing + CXL group. The mean uncorrected distance visual acuity (UDVA) improved from 0.79 ± 0.39 logMAR to 0.52 ± 0.31 logMAR (P < 0.05) in the MyoRing + CXL group and from 0.65 ± 0.38 logMAR to 0.62 ± 0.23 logMAR (P = 0.70) in the MyoRing group. CDVA changed from 0.33 ± 0.19 logMAR to 0.25 ± 0.16 logMAR (P = 0.10) in the MyoRing + CXL group and 0.32 ± 0.22 logMAR to 0.33 ± 0.17 logMAR (P > 0.50) in the MyoRing group. The mean keratometry (Km) decreased from 47.5 ± 2.7 D to 43.8 ± 3.2 D (P < 0.001) in the MyoRing group and 49.3 ± 3.4 D to 45.1 ± 3.0 D (P < 0.001) in the MyoRing + CXL group. Besides, horizontal coma was significantly lower in the MyoRing + CXL group (P = 0.022). Conclusion: MyoRing insertion combined with CXL is a safe and effective method for the treatment of keratoconus. The visual and topographic outcomes were comparable to that for MyoRing insertion after 10 months; however, horizontal coma was significantly lower in the MyoRing + CXL group. © 2020 Wolters Kluwer Medknow Publications. All rights reserved.
Related Docs
View other Related Docs
1. Updates on Corneal Collagen Cross-Linking: Indications, Techniques and Clinical Outcomes, Journal of Current Ophthalmology (2017)
2. Efficacy of Complete Rings (Myoring) in Treatment of Keratoconus: A Systematic Review and Meta-Analysis, International Ophthalmology (2019)
3. Clinical Outcomes of a New Type of Continuous Intrastromal Corneal Ring for Treatment of Keratoconus, Cornea (2022)
4. Intrastromal Corneal Ring Segment Implantation (Keraring 355°) in Patients With Central Keratoconus: 6-Month Follow-Up, Journal of Ophthalmology (2015)
5. Visual and Refractive Outcomes and Tomographic Changes After Femtosecond Laser-Assisted Intrastromal Corneal Ring Segment Implantation in Patients With Keratoconus, Journal of Ophthalmic and Vision Research (2018)
6. Appropriate Sequence of Combined Intracorneal Ring Implantation and Corneal Collagen Cross-Linking in Keratoconus: A Systematic Review and Meta-Analysis, Cornea (2018)
7. Mini-Scleral Contact Lens for Management of Poor Visual Outcomes After Intrastromal Corneal Ring Segments Implantation in Keratoconus, Journal of Ophthalmic and Vision Research (2016)
8. Long-Term Results of Myoring Implantation in Patients With Keratoconus, Clinical and Experimental Optometry (2021)
Experts (# of related papers)
View all Related Experts
Mehrdad Mohammadpour (5)
Masoud Khorrami-Nejad (4)
Other Related Docs
9. Updates on Managements for Keratoconus, Journal of Current Ophthalmology (2018)
10. Efficacy of Myoring Implantation in the Treatment of Keratoconus; [Myoring 植入术治疗圆锥角膜的疗效观察], International Eye Science (2024)
11. Comparison of Visual, Tomographic, and Biomechanical Outcomes of 360 Degrees Intracorneal Ring Implantation With and Without Corneal Crosslinking for Progressive Keratoconus: A 5-Year Follow-Up, Cornea (2021)
12. Comparison of Two Different 360-Degree Intrastromal Corneal Rings Combined With Simultaneous Accelerated-Corneal Cross-Linking, European Journal of Ophthalmology (2024)
13. Visual, Keratometric and Corneal Biomechanical Changes After Intacs Sk Implantation for Moderate to Severe Keratoconus, Journal of Ophthalmic and Vision Research (2016)
14. Effect of Corneal Cone Location on Corneal Curvature Changes and Uncorrected Distance Visual Acuity After Corneal Collagen Cross-Linking for Progressive Keratoconus: A One-Year Survey, Biosciences Biotechnology Research Asia (2015)
15. Mesopic Quality of Vision After Accelerated 18 Mw/Cm2 Corneal Cross-Linking: Mid-Term Results, Middle East African Journal of Ophthalmology (2017)
16. Corneal Cross-Linking Treatment of Keratoconus, Oman Journal of Ophthalmology (2015)
17. Corneal Collagen Cross-Linking in the Treatment of Progressive Keratoconus: A Randomized Controlled Contralateral Eye Study, Middle East African Journal of Ophthalmology (2015)
18. Technique of Simultaneous Femtosecond Laser Assisted Myoring Implantation and Accelerated Intrastromal Collagen Cross-Linking for Management of Progressive Keratoconus: A Novel Technique, Contact Lens and Anterior Eye (2016)
19. Microbial Keratitis Following Intracorneal Ring Implantation, Clinical and Experimental Optometry (2019)
20. Mesopic Visual Quality After Accelerated Corneal Cross Linking: A 12-Month Follow-Up Study, Journal of Current Ophthalmology (2017)
21. Comparison of the Myoring Implantation Depth by Mechanical Dissection Using Pocketmaker Microkeratome Versus Melles Hook Via As-Oct, BMC Ophthalmology (2018)
22. Short-Term Comparison of Accelerated and Standard Methods of Corneal Collagen Crosslinking, Journal of Cataract and Refractive Surgery (2015)