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Multifunctional Magnetic Nanoparticles-Labeled Mesenchymal Stem Cells for Hyperthermia and Bioimaging Applications Publisher Pubmed



Ghorbanzade S1 ; Naghib SM1 ; Sadr A2 ; Fateminia FS1, 3 ; Ghaffarinejad A4, 5 ; Majidzadeha K3 ; Sanatinezhad A6, 7
Authors

Source: Methods in Molecular Biology Published:2020


Abstract

Magnetic nanoparticles have demonstrated considerable capacity for theranosis purposes due to their unique characteristics, including magnetic properties, comparable size to biomolecules, favorable conjugations of drugs and biomolecules, ability to labeling, and capability of sensing, separation, detection, and targeted drug delivery. They could be exploited in magnetic resonance imaging as the contrast agents and also warmed as exposed to an external magnetic AC field that could be applied in hyperthermia. Here, progresses and advances in the strategy and assembly of fluorescent magnetic nanoparticles are presented for stem cell tracing and drugs/biomolecules targeting into cells. © 2019, Springer Science+Business Media New York.
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