3D in Vitro Cancerous Tumor Models: Using 3D Printers

3D in Vitro Cancerous Tumor Models: Using 3D Printers Publisher Pubmed

Zaheditabar Z¹ ; Bagherikhoulenjani S¹ ; Mirzadeh H¹ ; Amanpour S²

Show Affiliations

1. Department of Polymer and Color Engineering, Amirkabir University of Technology, P.O. Box: 15875-4413, Iran
2. Cancer Biology Research Center, Tehran University of Medical Sciences, P.O. Box: 14197-33141, Iran

Source: Medical Hypotheses Published:2019

Abstract

Recently, magnetic Hyperthermia is one of the promising methods for cancer treatments. In this method by applying magnetic fields and generating heat, cancerous tissues are eliminated. The degree and pattern of generated heat in cancerous and adjacent non-cancerous tissues plays an important role on the outcome of the treatment. it is mainly affected by diffusion and distribution pattern of magnetic nanoparticles within the cancerous and non-cancerous tissues. Study the diffusion and distribution patterns of magnetic nanoparticle in vivo is difficult and costly in many cases and in some cases evaluating the amount of generated heat at cancer site is almost impossible. In vitro models for cancer tissues are alternatives for in vivo models. However, usual in vitro models could not resembling all the characteristics of a cancer tumor. In this hypothesis we propose that using 3D printers can provide a platform to fabricate a personalized in vitro cancer model which could simulate the most important features of the cancerous tissues (including shape and vascular network) and can be used to study magnetic hyperthermia in a simulated media of compatible to in vivo conditions. © 2019

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Style	Citing Format
MLA	Zaheditabar Z, et al.. "3D in Vitro Cancerous Tumor Models: Using 3D Printers." Medical Hypotheses, vol. 124, no. , 2019, pp. 91-94.
APA	Zaheditabar Z, Bagherikhoulenjani S, Mirzadeh H, Amanpour S (2019). 3D in Vitro Cancerous Tumor Models: Using 3D Printers. Medical Hypotheses, 124(), 91-94.
Chicago	Zaheditabar Z, Bagherikhoulenjani S, Mirzadeh H, Amanpour S. "3D in Vitro Cancerous Tumor Models: Using 3D Printers." Medical Hypotheses 124, no. (2019): 91-94.
Harvard	Zaheditabar Z et al. (2019) '3D in Vitro Cancerous Tumor Models: Using 3D Printers', Medical Hypotheses, 124(), pp. 91-94.
Vancouver	Zaheditabar Z, Bagherikhoulenjani S, Mirzadeh H, Amanpour S. 3D in Vitro Cancerous Tumor Models: Using 3D Printers. Medical Hypotheses. 2019;124():91-94.
BibTex	@article{ author = {Zaheditabar Z and Bagherikhoulenjani S and Mirzadeh H and Amanpour S}, title = {3D in Vitro Cancerous Tumor Models: Using 3D Printers}, journal = {Medical Hypotheses}, volume = {124}, number = {}, pages = {91-94}, year = {2019} }
RIS	TY - JOUR AU - Zaheditabar Z AU - Bagherikhoulenjani S AU - Mirzadeh H AU - Amanpour S TI - 3D in Vitro Cancerous Tumor Models: Using 3D Printers JO - Medical Hypotheses VL - 124 IS - SP - 91 EP - 94 PY - 2019 ER -

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