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The Hiv Treatment Cascade in People Living With Hiv in Iran in 2014: Mixed-Method Study to Measure Losses and Reasons Publisher Pubmed



Ghalehkhani N1 ; Farhoudi B2 ; Gouya MM3 ; Sharifi H1 ; Seyedalinaghi S4 ; Kamali K5 ; Fahimfar N5 ; Rajabpour Z5 ; Doostiirani A6 ; Sedaghat A7 ; Mirzazadeh A1, 8
Authors
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Authors Affiliations
  1. 1. HIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
  2. 2. Clinical Research Development Center, Amiralmomenin Hospital, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  3. 3. Iran University of Medical Sciences, Tehran, Iran
  4. 4. Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. HIV/AIDS Control Office, Center for Communicable Disease, Ministry of Health, Tehran, Iran
  6. 6. Department of Epidemiology, School of Public Health and Research Center for Health Sciences, Hamadan university of Medical Sciences, Hamadan, Iran
  7. 7. Iran Blood Transfusion, Tehran, Iran
  8. 8. Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States

Source: International Journal of STD and AIDS Published:2019


Abstract

The study assessed the HIV treatment cascade of people living with HIV (PLWH) in Iran and the reasons for gaps in HIV services in 2014. We did the cascade analysis using the WHO HIV test–treat–retain cascade analysis tool (2014). To measure the gaps, we checked the records for all PLWH reported to the national HIV surveillance till September 2014 to define how many were alive, linked to HIV care, assessed for CD4 cell count, started antiretroviral therapy (ART), and reported to be alive up to five years after ART. To assess the reasons for gaps in the cascade, we ran desk review, four focus group discussions and 51 in-depth interviews with key informants including PLWH. Spectrum model estimated 75,700 PLWH in Iran, of whom only 22,647 people (%30) were diagnosed. Of those who were diagnosed with HIV, 16,266 people (%72) had enrolled in HIV care. About 13% of all PLWH were retained in HIV care and only 9% (6745 people) had ever been tested for CD4 cell count. Only 8% (6018 people) of all PLWH had received ART by September 2014. We found the biggest gap in the HIV treatment cascade to be HIV diagnosis as only 30% of PLWH have been diagnosed. Innovative strategies to improve HIV testing, particularly those that work best for key populations, are critical to reach the 90–90-90 targets. © The Author(s) 2019.