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The Role of Mirnas in Covid-19 Disease Publisher



Fani M1 ; Zandi M2, 3 ; Ebrahimi S4 ; Soltani S2, 3 ; Abbasi S5
Authors
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Authors Affiliations
  1. 1. Department of Pathobiology and Laboratory Sciences, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
  2. 2. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Medical Microbiology, Faculty of Medicine Science, Kerman University of Medical Sciences, Kerman, Iran
  5. 5. Abadan Faculty of Medical Science, Abadan, Iran

Source: Future Virology Published:2021


Abstract

Nowadays, the SARS Coronavirus 2 (SARS-CoV-2) infection is recognized as the primary cause of mortality in humans. SARS-CoV-2 is transmitted through human-to-human contact and is asymptomatic in most patients. In addition to approved vaccines against SARS-CoV-2 infection, miRNAs may also be promising options against this new virus. miRNAs are small and noncoding RNAs 18-25 nucleotides in length that target the mRNAs to degrade them or obstruct their translation miRNAs act as an observer in cells. This study reviewed the literature on the potential role of cellular miRNAs in the SARS-CoV-2-host interplay as a therapeutic option in COVID-19 patients. © 2021 Future Medicine Ltd.. All rights reserved.