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Impact of Ige-Mediated Food Allergy on Parental Quality of Life in Iranian Patients Pubmed



Fathi SM1 ; Tavakol M2 ; Rezaei N3, 4 ; Movahedi M5 ; Aghamohammadi A3 ; Shariat M5 ; Sadeghi B3 ; Behniafard N6 ; Darabi B7 ; Hajikhani A8 ; Abdollapour I9, 10 ; Gharagozlou M5
Authors
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Authors Affiliations
  1. 1. Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
  2. 2. Department of Allergy and Clinical Immunology, Shahid Bahonar Hospital, Alborz University of Medical Sciences, Karaj, Iran
  3. 3. Molecular Immunology Research Center, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Research Center for Primary Immunodeficiency, Pediatrics Center of Excellence Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Allergy and Clinical Immunology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  7. 7. Department of Allergy and Clinical Immunology, Ilam University of Medical Sciences, Ilam, Iran
  8. 8. Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  9. 9. School of Public Health, Arak University of Medical Sciences, Arak, Iran
  10. 10. Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Allergy# Asthma and Immunology Published:2016


Abstract

Food allergy is a common disorder especially in the first years of life. Strict avoidance of the responsible food is the most effective therapeutic measure so far. But this continuous vigilance could be stressful for the patient and family and decreases their quality of life (QOL). This survey was designed to evaluate the impact of IgE-mediated food allergy on parental QOL in Iranian patients and to develop a valid Persian version of Food Allergy Quality Of Life-Parental Burden (FAQL-PB) questionnaire. 90 patients (28 females, 62 males) and their parents who were referred to the clinic of Allergy in Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran were enrolled. The questionnaire was translated with scientific method and its reliability was approved in a pilot study (ICC=0.75, cronbach-α=0.90). Among all patients the most common allergens were wheat (60%) and cow's milk (42%). The patient's age (p=0.02), parent's gender (p=0.004), mother's age (p=0.02), duration of the disease (p=0.048), and allergen multiplicity (p=0.004) were found to have the most significant correlation with family and social activity (FSA) domain. The most meaningful associations were achieved between parent's gender (p<0.001) and emotional issues (EM); as well as meal preparation (MP) with patient's age (p=0.02), parent's gender (p<0.0001) and also allergen multiplicity (p= 0.003); likewise nutrition and health concern (NH) domain with parent's gender (p<0.001). Anaphylaxis's history did not place any burden on each domain. It was concluded that presence of food allergic patients in families could considerably affect all domains of QOL. © Copyright Autumn 2016, Iran J Allergy Asthma Immunol. All rights reserved.
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