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Determination of the Most Common Indoor and Outdoor Allergens in 602 Patients With Allergic Symptoms Using Specific Ige Local Panel Pubmed



Shoormasti RS1 ; Pourpak Z1 ; Fazlollahi MR1 ; Shabani A1, 2 ; Kazemnejad A3 ; Ebadi Z1 ; Tayebi B1 ; Darabi B4 ; Movahedi M5 ; Mahdaviani SA6 ; Moin M1, 5
Authors
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Authors Affiliations
  1. 1. Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Virtual School of Tehran, University of Medical Sciences, Tehran, Iran
  3. 3. Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  4. 4. Department of Pediatrics, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
  5. 5. Department of Allergy and Clinical Immunology, Children Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Allergy# Asthma and Immunology Published:2017


Abstract

Aeroallergens play an important role in developing allergic diseases. The aim of this study was to determine the outdoor and indoor sensitization using a specific regional panel of aeroallergens in allergic patients. All patients with allergic symptoms referred to Immunology, Asthma and Allergy Research Institute (IAARI) in Tehran, Iran from December 2010 to July 2013 entered this cross sectional study. We evaluated serum samples for specific IgE against 20 selected aeroallergens provided by a specific panel (RIDA Allergy Screen test, IAARI panel). A p value less than 0.05 was considered as significant. The patients (n=602) were 49.8 % male and 50.2% female. The median age was 9 years. Positive specific IgE at least to one allergen was 53.2%. The percentages of patients with only outdoor or indoor sensitization were 37.5 and 19.7%, respectively. Moreover, 42.8% showed sensitization to both indoor and outdoor aeroallergens. The most common outdoor aeroallergens in decreasing order were plane tree (32.8%), Bermuda grass (32.2%), timothy grass (30.6%), saltwort (28.4%). The percentage of specific IgE to indoor allergens including mold and mite were 23.8 % and 22.2%, respectively. There was a statistically significant relationship between specific IgE to timothy grass and mold allergens between two genders (p=0.04 and p=0.02, respectively). The results of this study shows that outdoor aeroallergens can be considered as the most common causes of allergic symptoms in our allergic patients. Copyright © Summer 2017, Iran J Allergy Asthma Immunol. All rights reserved.
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