Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis

Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis Publisher Pubmed

Rahimiesboei B¹ ; Zarei M² ; Mohebali M¹ ; Valian HK¹ ; Shojaee S¹ ; Mahmoudzadeh R² ; Salabati M²

Show Affiliations

1. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
2. Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Korean Journal of Parasitology Published:2018

Abstract

This prospective study was aimed to detect acute and chronic ocular toxoplasmosis by comparison of anti-Toxoplasma gondii IgM and IgG antibody levels and IgG avidity test. One hundred and seventeen patients with ocular toxoplasmosis (OT) who referred to the Farabi Eye Hospital, Tehran, Iran were included in this study. Of the patients, 77 cases were positive for anti-T. gondii IgG, and 8 cases were positive for anti-T. gondii IgM. IgG avidity test revealed 11, 4, and 102 cases were low, intermediate, and high, respectively, and 6.8% and 9.4% of cases were positive for IgM and IgG avidity tests, respectively (P = 0.632). Agreement (Kappa value) between paired tests IgG-IgM, IgG-IgG avidity, and IgM-IgG avidity was 0.080, 0.099, and 0.721, respectively (P < 0.05). This study showed that conventional serologic tests (IgM and IgG levels) and IgG avidity correlate well each other and can be used to differentiate recent infections from old OT. It seems that reactivated old infections rather than recently acquired infections are majority of Iranian OT patients. © 2018, Korean Society for Parasitology and Tropical Medicine.

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Hossein Keshavarz Valian (11)

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Style	Citing Format
MLA	Rahimiesboei B, et al.. "Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis." Korean Journal of Parasitology, vol. 56, no. 2, 2018, pp. 147-152.
APA	Rahimiesboei B, Zarei M, Mohebali M, Valian HK, Shojaee S, Mahmoudzadeh R, Salabati M (2018). Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis. Korean Journal of Parasitology, 56(2), 147-152.
Chicago	Rahimiesboei B, Zarei M, Mohebali M, Valian HK, Shojaee S, Mahmoudzadeh R, Salabati M. "Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis." Korean Journal of Parasitology 56, no. 2 (2018): 147-152.
Harvard	Rahimiesboei B et al. (2018) 'Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis', Korean Journal of Parasitology, 56(2), pp. 147-152.
Vancouver	Rahimiesboei B, Zarei M, Mohebali M, Valian HK, Shojaee S, Mahmoudzadeh R, et al.. Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis. Korean Journal of Parasitology. 2018;56(2):147-152.
BibTex	@article{ author = {Rahimiesboei B and Zarei M and Mohebali M and Valian HK and Shojaee S and Mahmoudzadeh R and Salabati M}, title = {Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis}, journal = {Korean Journal of Parasitology}, volume = {56}, number = {2}, pages = {147-152}, year = {2018} }
RIS	TY - JOUR AU - Rahimiesboei B AU - Zarei M AU - Mohebali M AU - Valian HK AU - Shojaee S AU - Mahmoudzadeh R AU - Salabati M TI - Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis JO - Korean Journal of Parasitology VL - 56 IS - 2 SP - 147 EP - 152 PY - 2018 ER -

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