Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma

Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma Publisher Pubmed

Mohammadi M¹ ; Mohammadi SS¹ ; Tabatabaei SM¹ ; Eslami Y¹ ; Zarei R¹ ; Zandvakil N² ; Fakhraie G¹ ; Safizadeh M¹ ; Farshchi MR³ ; Moghimi S³

Show Affiliations

1. Glaucoma Service, Ophthalmology Department, Farabi Eye Hospital, Tehran University of Medical Sciences, Iran
2. Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran
3. Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California, La Jolla, San Diego, 92093, CA, United States

Source: Journal of Glaucoma Published:2022

Abstract

Purpose: To compare the pattern of vascular density and structural damage in primary open angle glaucoma (POAG) with primary angle closure glaucoma (PACG) using optical coherence tomography (OCT) and OCT angiography (OCTA) in the optic nerve head, circumpapillary, and macular regions, respectively. Materials and Methods: One hundred thirty-one eyes of 82 patients (53 eyes with PACG and 78 eyes with POAG) were enrolled in this study. The patients underwent complete ophthalmic examination, Bruch membrane opening minimum rim width, circumpapillay retinal nerve fiber layer (cpRNFL), and macular ganglion cell complex (GCC) measurements and vascular density determination of the peripapillary and macular area with OCT and OCTA. A linear mixed model was used for the statistical analysis. Results: There was no significant difference between the 2 groups in terms of age (P=0.94) and visual field mean deviation (P=0.78). Female-to-male ratio was higher in PACG patients than the POAG group (P=0.02), and AL was shorter in PACG eyes (P<0.001). cpRNFL and GCC were not different between the 2 groups (all P values>0.05, except for nasal segment cpRNFL). Vessel densities in the peripapillary and macular areas were comparable between the 2 groups (all P values>0.05). Although Bruch membrane opening minimum rim width was thicker in PACG eyes on univariate analysis, the multivariable analysis showed no significant difference between the 2 groups (P>0.05). Conclusions: PACG and POAG eyes with similar visual field damages have comparable structural damage patterns in the peripapillary and inner macular thickness and vessel density measurements. © 2022 Lippincott Williams and Wilkins. All rights reserved.

Related Docs

View other Related Docs

1. An Update on Therapeutic Modalities for the Prevention of Angle Closure Glaucoma, Current Opinion in Ophthalmology (2017)

2. Prevalence and Risk Factors of Glaucoma in an Adult Population From Shahroud, Iran, Journal of Current Ophthalmology (2019)

3. Qualitative Evaluation of Anterior Segment in Angle Closure Disease Using Anterior Segment Optical Coherence Tomography, Journal of Current Ophthalmology (2016)

4. The Distribution of Vertical Cup-To-Disc Ratio and Its Determinants in the Iranian Adult Population, Journal of Current Ophthalmology (2020)

5. Comparison of Anterior Chamber Parameters in Patients With Plateau Iris Configuration and Pupillary Block Using Asoct, Journal of Glaucoma (2017)

6. Parapapillary Choroidal Microvascular Density in Acute Primary Angle-Closure and Primary Open-Angle Glaucoma: An Optical Coherence Tomography Angiography Study, British Journal of Ophthalmology (2023)

7. Lens Position Parameters As Predictors of Intraocular Pressure Reduction After Cataract Surgery in Glaucomatous Versus Nonglaucomatous Eyes, Investigative Ophthalmology and Visual Science (2016)

8. Six-Month Outcomes of Combined Conventional Needle Goniotomy and Phacoemulsification in Eyes With Early to Moderate Primary Open-Angle and Pseudoexfoliation Glaucoma and Ocular Hypertension, Indian Journal of Ophthalmology (2022)

Experts (# of related papers)

View all Related Experts

Masoud Mohammadi (5)

Mona Seyed Safizadeh (4)

Style	Citing Format
MLA	Mohammadi M, et al.. "Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma." Journal of Glaucoma, vol. 31, no. 8, 2022, pp. 645-650.
APA	Mohammadi M, Mohammadi SS, Tabatabaei SM, Eslami Y, Zarei R, Zandvakil N, Fakhraie G, Safizadeh M, Farshchi MR, Moghimi S (2022). Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma. Journal of Glaucoma, 31(8), 645-650.
Chicago	Mohammadi M, Mohammadi SS, Tabatabaei SM, Eslami Y, Zarei R, Zandvakil N, Fakhraie G, Safizadeh M, Farshchi MR, Moghimi S. "Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma." Journal of Glaucoma 31, no. 8 (2022): 645-650.
Harvard	Mohammadi M et al. (2022) 'Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma', Journal of Glaucoma, 31(8), pp. 645-650.
Vancouver	Mohammadi M, Mohammadi SS, Tabatabaei SM, Eslami Y, Zarei R, Zandvakil N, et al.. Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma. Journal of Glaucoma. 2022;31(8):645-650.
BibTex	@article{ author = {Mohammadi M and Mohammadi SS and Tabatabaei SM and Eslami Y and Zarei R and Zandvakil N and Fakhraie G and Safizadeh M and Farshchi MR and Moghimi S}, title = {Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma}, journal = {Journal of Glaucoma}, volume = {31}, number = {8}, pages = {645-650}, year = {2022} }
RIS	TY - JOUR AU - Mohammadi M AU - Mohammadi SS AU - Tabatabaei SM AU - Eslami Y AU - Zarei R AU - Zandvakil N AU - Fakhraie G AU - Safizadeh M AU - Farshchi MR AU - Moghimi S TI - Comparison of Vascular Density and Structural Patterns Between Primary Open Angle Glaucoma and Primary Angle Closure Glaucoma JO - Journal of Glaucoma VL - 31 IS - 8 SP - 645 EP - 650 PY - 2022 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract