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The Role of Bacterial and Fungal Human Respiratory Microbiota in Covid-19 Patients Publisher Pubmed



Soltani S1, 2 ; Zakeri A3 ; Zandi M1 ; Kesheh MM4 ; Tabibzadeh A4 ; Dastranj M5 ; Faramarzi S6 ; Didehdar M7 ; Hafezi H8 ; Hosseini P1 ; Farahani A5
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Hematology, School of Medicine, Tarbiat Modares University, Tehran, Iran
  4. 4. Department of Virology, School of Medicine, Iran University of Medical Science, Tehran, Iran
  5. 5. Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
  6. 6. Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran
  7. 7. Department of Medical Parasitology and Mycology, School of Medicine, Arak University of Medical Sciences, Arak, Iran
  8. 8. Department of Dermatology, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Source: BioMed Research International Published:2021


Abstract

Recently, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of coronavirus disease 2019 (COVID-19), has led to a worldwide pandemic with millions of infected patients. Alteration in humans' microbiota was also reported in COVID-19 patients. The alteration in human microbiota may contribute to bacterial or viral infections and affect the immune system. Moreover, human's microbiota can be altered due to SARS-CoV-2 infection, and these microbiota changes can indicate the progression of COVID-19. While current studies focus on the gut microbiota, it seems necessary to pay attention to the lung microbiota in COVID-19. This study is aimed at reviewing respiratory microbiota dysbiosis among COVID-19 patients to encourage further studies on the field for assessment of SARS-CoV-2 and respiratory microbiota interaction. © 2021 Saber Soltani et al.
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