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Dietary Antioxidant Index and the Risk of Recurrent Aphthous Stomatitis Publisher Pubmed



Mohseni GK1 ; Azaryan F2 ; Kamali M3 ; Tavakoli A4 ; Mahmoudi Z5 ; Mirshafaei MA6 ; Mobarakeh KA7 ; Mohammadi S8 ; Saeedirad Z9 ; Ataei Kachooei M10 ; Khoshdooz S6 ; Omidi S11 ; Doaei S12 ; Gholamalizadeh M13
Authors
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Authors Affiliations
  1. 1. Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  2. 2. Department of Physiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
  3. 3. School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
  6. 6. Department of Sport Physiology, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran
  7. 7. Department of Community Nutrition, Nutrition and Food Security Research Center, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  8. 8. Health Department, Zanjan University of Medical Sciences, Zanjan, Iran
  9. 9. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  10. 10. Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
  11. 11. Department of Health Education and Promotion, Research Center of Health and Environment, School of Health, Guilan University of Medical Sciences, Rasht, Iran
  12. 12. Department of Community Nutrition, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  13. 13. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: International Dental Journal Published:2025


Abstract

Background: Recurrent aphthous stomatitis (RAS) is a common condition that affects the oral mucosa. Antioxidants are crucial in neutralizing free radicals in the body and may have a preventive role against RAS. This study aims to examine the association between dietary antioxidant index (DAI) and RAS occurrence. Methods: This cross-sectional study was conducted on 144 individuals with RAS and 135 individuals without RAS. The dietary intake of the participants was assessed using the food frequency questionnaire. The DAI was applied to measure the antioxidant capacity of the diet. Logistic regression models were applied to assess the link between RAS and DAI after adjusting the confounding variables. Results: There was a significant negative association between RAS and DAI of zinc (OR = 0.639, CI95%: 0.456-0.896, P = .009) and total score of DAI (OR = 0.802, CI95%: 0.682-0.944, P = .008) after adjustment for age. The results remained significant after further adjustment for body mass index and calorie intake. Conclusion: The present study indicated a possible negative association between the risk of RAS and the DAI score as a measure of the antioxidant potential of diet. Further studies are warranted. © 2024 The Authors
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