Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews

Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share this content! On (X network) By

Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews Publisher Pubmed

Grindem H¹ ; Mansournia MA^{2, 3} ; Oiestad BE⁴ ; Ardern CL^{5, 6}

Show Affiliations

1. Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway
2. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
3. Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway
5. Division of Physiotherapy, Linkoping University, Linkoping, Sweden
6. School of Allied Health, La Trobe University, Melbourne, VIC, Australia

Source: British Journal of Sports Medicine Published:2019

Abstract

[No abstract available]

Related Docs

View other Related Docs

1. The Effects of Cycling With and Without Functional Electrical Stimulation on Lower Limb Dysfunction in Patients Post-Stroke: A Systematic Review With Meta-Analysis, NeuroRehabilitation (2019)

2. Association Between Gout and the Development of Parkinson’S Disease: A Systematic Review and Meta-Analysis, BMC Neurology (2022)

3. The Effect of Alcohol on Osteoporosis: A Systematic Review and Meta-Analysis, Drug and Alcohol Dependence (2019)

4. Herbal Medicines for Type 1 Diabetes Mellitus, Cochrane Database of Systematic Reviews (2015)

5. Efficacy of Gut–Brain Neuromodulators in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis, The Lancet Gastroenterology and Hepatology (2025)

6. Prevalence of Developmental Dyslexia Among Primary School Children in Iran: A Systematic Review and Meta-Analysis, Iranian Journal of Psychiatry (2025)

7. Spatial Distribution of Common Pathogenic Human Intestinal Protozoa in Iran: A Systematic Review, Iranian Journal of Public Health (2021)

8. Efficacy of L-Carnitine Supplementation for Management of Blood Lipids: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials, Nutrition# Metabolism and Cardiovascular Diseases (2019)

Experts (# of related papers)

View all Related Experts

Pejman Rohani (15)

Sakineh Shab-Bidar (14)

Other Related Docs

9. Effects of Whey Protein on Glycemic Control and Serum Lipoproteins in Patients With Metabolic Syndrome and Related Conditions: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials, Lipids in Health and Disease (2020)

10. Impact of Omega-3 Supplementation on Homocysteine Levels in Humans: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials, Nutrition# Metabolism and Cardiovascular Diseases (2022)

11. Safety and Effectiveness of Enhanced External Counterpulsation (Eecp) in Refractory Angina Patients: A Systematic Reviews and Meta-Analysis, Journal of Cardiovascular and Thoracic Research (2021)

12. A Posteriori Dietary Patterns and Metabolic Syndrome in Adults: A Systematic Review and Meta-Analysis of Observational Studies, Public Health Nutrition (2018)

13. The Diagnostic Values of Uch-L1 in Traumatic Brain Injury: A Meta-Analysis, Brain Injury (2018)

14. Aquatic Therapy for Improving Lower Limbs Function in Post-Stroke Survivors: A Systematic Review With Meta-Analysis, Topics in Stroke Rehabilitation (2021)

15. Triglyceride-Glucose Index and Heart Failure: A Systematic Review and Meta-Analysis, Cardiovascular Diabetology (2023)

16. Beneficial Effects of L-Carnitine Supplementation for Weight Management in Overweight and Obese Adults: An Updated Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials, Pharmacological Research (2020)

17. Effects of Pistachios on Glycaemic Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials, British Journal of Nutrition (2023)

18. Effects of Grape Products on Blood Lipids: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials, Food and Function (2019)

19. Desmopressin Effectiveness in Renal Colic Pain Management: Systematic Review and Meta-Analysis, American Journal of Emergency Medicine (2016)

20. The Effects of Green Tea Extract Supplementation on Body Composition, Obesity-Related Hormones and Oxidative Stress Markers: A Grade-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomised Controlled Trials, British Journal of Nutrition (2024)

21. The Effects of Vitamin C Supplementation on Glycemic Control in Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis, Diabetes and Metabolic Syndrome: Clinical Research and Reviews (2023)

22. Impact of Red Yeast Rice Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized-Controlled Trials, Expert Review of Clinical Pharmacology (2023)

23. Association Between Sleep Duration and Hypertension Incidence: Systematic Review and Meta-Analysis of Cohort Studies, PLoS ONE (2024)

24. Biases in Randomized Trials, Epidemiology (2017)

25. Quality of Life in Elderly Iranian Population Using Leiden-Padua Questionnaire: A Systematic Review and Meta-Analysis, International Journal of Preventive Medicine (2017)

26. Evaluation of the Safety and Efficacy of Direct Oral Anticoagulants Compared With Vitamin-K Antagonists in the Treatment of Left Ventricular Thrombosis. a Systematic Review and Meta-Analysis, Heart and Lung (2024)

27. Efficacy and Safety of Ppar Agonists in Primary Biliary Cholangitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, BMC Gastroenterology (2025)

28. Complications of Stent Placement in Patients With Esophageal Cancer: A Systematic Review and Network Meta-Analysis, PLoS ONE (2017)

29. The Efficacy of Low Glycemic Index Diet on Seizure Frequency in Pediatric Patients With Epilepsy: A Systematic Review and Meta-Analysis, Seizure (2024)

30. Dietary Intake of Total, Animal and Plant Proteins and the Risk of Coronary Heart Disease and Hypertension: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies, Critical Reviews in Food Science and Nutrition (2022)

31. Prevalence of Dental Caries and Fluoride Concentration of Drinking Water: A Systematic Review, Dental Research Journal (2017)

32. The Effects of Pomegranate Consumption on Obesity Indices in Adults: A Systematic Review and Meta-Analysis, Food Science and Nutrition (2024)

33. The Association Between Types of Seafood Intake and the Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies, Health Promotion Perspectives (2019)

34. Association Between Total and Animal Proteins With Risk of Fracture: A Systematic Review and Dose–Response Meta-Analysis of Cohort Studies, Osteoporosis International (2024)

35. Safety and Efficacy of Two Different Doses of Everolimus in Kidney Transplantation: A Systematic Review and Meta-Analysis, Iranian Journal of Kidney Diseases (2017)

36. The Effectiveness of Nonsurgical Interventions for Weight Loss Maintenance in Adults: An Updated, Grade-Assessed Systematic Review and Meta-Analysis of Randomized Clinical Trials, Nutrition Reviews (2025)

37. Effect of Carbohydrate Restriction on Body Weight in Overweight and Obese Adults: A Systematic Review and Dose–Response Meta-Analysis of 110 Randomized Controlled Trials, Frontiers in Nutrition (2023)

38. Protective Effects of Melatonin Against Oxidative Stress Induced by Metabolic Disorders in the Male Reproductive System: A Systematic Review and Meta-Analysis of Rodent Models, Frontiers in Endocrinology (2023)

39. Prevalence of Preeclampsia and Eclampsia in Iran, Archives of Iranian Medicine (2016)

40. The Effects of Weight Loss Interventions on Children and Adolescents With Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis, Obesity Science and Practice (2024)

41. Newborn Screening for Galactosaemia, Cochrane Database of Systematic Reviews (2017)

42. Effectiveness of Low-Fat Diet on the Levels of Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Proteins: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials, Journal of Health, Population and Nutrition (2024)

43. The Effects of Silymarin Consumption on Inflammation and Oxidative Stress in Adults: A Systematic Review and Meta-Analysis, Inflammopharmacology (2024)

44. The Association Between Total Protein, Animal Protein, and Animal Protein Sources With Risk of Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis of Cohort Studies, Advances in Nutrition (2023)

45. Simultaneous Comparison of Efficacy and Adverse Events of Interventions for Patients With Esophageal Cancer: Protocol for a Systematic Review and Bayesian Network Meta-Analysis, Asian Pacific Journal of Cancer Prevention (2016)

46. A Systematic Review and Meta-Analysis of Hymenolepis Nana in Human and Rodent Hosts in Iran: A Remaining Public Health Concern, Comparative Immunology# Microbiology and Infectious Diseases (2021)

47. The Effect of Weight Loss Therapies on Sirtuin 1 Regulation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, BMC Nutrition (2024)

48. Efficacy and Safety of Oral Alpha-Lipoic Acid Supplementation for Type 2 Diabetes Management: A Systematic Review and Dose– Response Meta-Analysis of Randomized Trials, Endocrine Connections (2022)

49. Statins in Adult Patients With Hiv, Medicine (United States) (2018)

50. Impact of Curcumin Supplementation on Radiation Dermatitis Severity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Asian Pacific Journal of Cancer Prevention (2023)

Style	Citing Format
MLA	Grindem H, et al.. "Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews." British Journal of Sports Medicine, vol. 53, no. 7, 2019, pp. 399-401.
APA	Grindem H, Mansournia MA, Oiestad BE, Ardern CL (2019). Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews. British Journal of Sports Medicine, 53(7), 399-401.
Chicago	Grindem H, Mansournia MA, Oiestad BE, Ardern CL. "Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews." British Journal of Sports Medicine 53, no. 7 (2019): 399-401.
Harvard	Grindem H et al. (2019) 'Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews', British Journal of Sports Medicine, 53(7), pp. 399-401.
Vancouver	Grindem H, Mansournia MA, Oiestad BE, Ardern CL. Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews. British Journal of Sports Medicine. 2019;53(7):399-401.
BibTex	@article{ author = {Grindem H and Mansournia MA and Oiestad BE and Ardern CL}, title = {Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews}, journal = {British Journal of Sports Medicine}, volume = {53}, number = {7}, pages = {399-401}, year = {2019} }
RIS	TY - JOUR AU - Grindem H AU - Mansournia MA AU - Oiestad BE AU - Ardern CL TI - Was It a Good Idea to Combine the Studies? Why Clinicians Should Care About Heterogeneity When Making Decisions Based on Systematic Reviews JO - British Journal of Sports Medicine VL - 53 IS - 7 SP - 399 EP - 401 PY - 2019 ER -